3-[4-(1H-indol-3-yl)butanoylamino]propanoic Acid | 137629-37-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-[4-(1H-indol-3-yl)butanoylamino]propanoic Acid
• CAS: 137629-37-9
• 化学式: C₁₅H₁₈N₂O₃
• 分子量: 274.31
• InChiKey: NHQSQRLCMSTADH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  82.2
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• METHODS FOR CONTROLLING GIBBERELLIN LEVELS
  申请人：ARNOLD WHITE & DURKEE

  公开号：US20020053095A1

  公开（公告）日：2002-05-02

  Methods and materials are disclosed for the inhibition and control of gibberellic acid levels. In particular, nucleic acid sequences of copalyl diphosphate synthase, 3-&bgr; hydroxylase, and 2-oxidase and additional nucleic acid sequences are disclosed. Gibberellic acid levels may be inhibited or controlled by preparation of a chimeric expression construct capable of expressing a RNA or protein product which suppresses the gibberellin biosynthetic pathway sequence, diverts substrates from the pathway or degrades pathway substrates or products. The sequence is preferably a copalyl diphosphate synthase sequence, a 3&bgr;-hydroxylase sequence, a 2-oxidase sequence, a phytoene synthase sequence, a C20-oxidase sequence, and a 2&bgr;,3&bgr;-hydroxylase sequence. Administration of a complementing agent, preferably a gibberellin or gibberellin precursor or intermediate restores bioactivity.

  本研究公开了抑制和控制赤霉素水平的方法和材料。特别是公开了 copalyl diphosphate synthase、3-&bgr; hydroxylase 和 2-oxidase 的核酸序列和其他核酸序列。赤霉素水平可以通过制备嵌合表达构建体来抑制或控制，该构建体能够表达抑制赤霉素生物合成途径序列、转移途径底物或降解途径底物或产物的 RNA 或蛋白质产物。该序列最好是共醛基二磷酸合成酶序列、3&bgr;-羟化酶序列、2-氧化酶序列、植物烯合成酶序列、C20-氧化酶序列和 2&bgr;,3&bgr;-羟化酶序列。施用补充剂，最好是赤霉素或赤霉素前体或中间体，可恢复生物活性。
• Methods for controlling gibberellin levels
  申请人：Brown M. Sherri

  公开号：US20070174931A1

  公开（公告）日：2007-07-26

  Methods and materials are disclosed for the inhibition and control of gibberellic acid levels. In particular, nucleic acid sequences of copalyl diphosphate synthase. 3-β hydroxylase, and 2-oxidase and additional nucleic acid sequences are disclosed. Gibberellic acid levels may be inhibited or controlled by preparation of a chimeric expression construct capable of expressing a RNA or protein product which suppresses the gibberellin biosynthetic pathway sequence, diverts substrates from the pathway or degrades pathway substrates or products. The sequence is preferably a copalyl diphosphate synthase sequence, a 3β-hydroxylase sequence, a 2-oxidase sequence, a phytoene synthase sequence, a C20-oxidase sequence, and a 2β,3β-hydroxylase sequence. Administration of a complementing agent, preferably a gibberellin or gibberellin precursor or intermediate restores bioactivity.
• US6723897B2
  申请人：——

  公开号：US6723897B2

  公开（公告）日：2004-04-20
• [EN] METHODS FOR CONTROLLING GIBBERELLIN LEVELS<br/>[FR] METHODE DE REGULARISATION DU TAUX DE GIBBERELLINE
  申请人：MONSANTO CO

  公开号：WO2000009722A2

  公开（公告）日：2000-02-24

  Methods and materials are disclosed for the inhibition and control of gibberellic acid levels. In particular, nucleic acid sequences of copalyl diphosphate synthase, 3-β hydroxylase, and 2-oxidase and additional nucleic acid sequences are disclosed. Gibberellic acid levels may be inhibited or controlled by preparation of a chimeric expression construct capable of expressing a RNA or protein product which suppresses the gibberellin biosynthetic pathway sequence, diverts substrates from the pathway or degrades pathway substrates or products. The sequence is preferably a copalyl diphosphate synthase sequence, a 3β-hydroxylase sequence, a 2-oxidase sequence, a phytoene synthase sequence, a C20-oxidase sequence, and a 2β,3β-hydroxylase sequence. Administration of a complementing agent, preferably a gibberellin or gibberellin precursor or intermediate restores bioactivity.