Ethyl 2-[[1-[2-[(7-chloroquinolin-4-yl)amino]ethylamino]-4-(diethoxymethylamino)-1-oxopentan-2-yl]amino]acetate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Ethyl 2-[[1-[2-[(7-chloroquinolin-4-yl)amino]ethylamino]-4-(diethoxymethylamino)-1-oxopentan-2-yl]amino]acetate
• 英文别名: ethyl 2-[[1-[2-[(7-chloroquinolin-4-yl)amino]ethylamino]-4-(diethoxymethylamino)-1-oxopentan-2-yl]amino]acetate
• 化学式: C₂₅H₃₈ClN₅O₅
• 分子量: 524.1
• InChiKey: USLVJJNHGYAZLW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  36
• 可旋转键数：
  18
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  123
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• ANTI-PLAQUE ORAL COMPOSITIONS
  申请人：Bhushan, Rajiv

  公开号：EP2934694A1

  公开（公告）日：2015-10-28
• ANTIMICROBIAL COMPOSITIONS
  申请人：Bhushan, Rajiv

  公开号：EP2941128A2

  公开（公告）日：2015-11-11
• EP3749294A1
  申请人：——

  公开号：EP3749294A1

  公开（公告）日：2020-12-16
• [EN] ANTIMICROBIAL COMPOSITIONS<br/>[FR] COMPOSITIONS ANTIMICROBIENNES
  申请人：BHUSHAN RAJIV

  公开号：WO2014100777A2

  公开（公告）日：2014-06-26

  An anti-microbial composition, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sufonyl Methane; MSM) is provided. Together, the combination of the two substances unexpectedly and beneficially inhibits bacterial or fungal biofilms when administered to an area of microbial infection. Preferred formulations include spray, lotion, solution, gel, cream, ointment, soap, deodorant, surgical rinse, or dental rinse.
• [EN] ANTI-PLAQUE ORAL COMPOSITIONS<br/>[FR] COMPOSITIONS ORALES ANTI-PLAQUE DENTAIRE
  申请人：BHUSHAN RAJIV

  公开号：WO2014100775A1

  公开（公告）日：2014-06-26

  An antiplaque oral composition, such as a toothpaste, gel dentifrice, tooth powder, mouth-rinse or mouthwash, tooth hardener, anti-calculus composition, gum or lozenge, comprising a chelator (such as EDTA and its salts), and a transport enhancer (such as Methyl Sulfonyl Methane; MSM) are provided. Together, the combination of the two substances unexpectedly and beneficially removes dental plaque when brushed or applied on teeth and gums. Preferred compositions are toothpastes, gel dentifrices and mouth-rinses or mouthwashes. Also provided are processes of repeatedly applying such antiplaque oral compositions to the teeth to obtain the antiplaque benefits mentioned.