1-bromomethylanthraquinone | 83236-53-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1-bromomethylanthraquinone
• 英文别名: 1-(Bromomethyl)anthracene-9,10-dione
• CAS: 83236-53-7
• 化学式: C₁₅H₉BrO₂
• 分子量: 301.139
• InChiKey: ZIAQIHPONXZRSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-bromomethylanthraquinone 以 二甲基亚砜 为溶剂， 反应 2.0h， 生成 1-methyl-2-methoxycarbonyl-6H-anthra<9,1-bc>pyrrol-6-one
  参考文献：
  名称：

  Gorelik, M. V.; Alimova, R. A., Journal of Organic Chemistry USSR (English Translation), 1984, vol. 20, # 7, p. 1415 - 1422

  摘要：

  DOI：
• 作为产物：
  描述：

  1-methylanthraquinone 在 过氧化苯甲酰 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氯化碳 为溶剂， 以75%的产率得到1-bromomethylanthraquinone
  参考文献：
  名称：

  Gorelik, M. V.; Alimova, R. A., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, p. 1556 - 1557

  摘要：

  DOI：

文献信息

• [EN] AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS<br/>[FR] ANTIMICROBIENS ET ANTINÉOPLASIQUES DE SELS D'AZOLIUM ET DE PURINIUM
  申请人：UNIV AKRON

  公开号：WO2012149523A1

  公开（公告）日：2012-11-01

  Singly and multiply charged imidazolium cations (ICs) have been identified as a class of chemical compositions that possess potent antineoplastic, antibacterial and antimicrobial properties. The imidazolium cations disclosed demonstrate greater or equivalent potency towards cancerous cells as the current clinical standard, cisplatin. These imidazolium cations, however, achieve this efficacy without any of the known toxic side effects caused by heavy metal-based antineoplastic drugs such as cisplatin.

  单电荷和多电荷咪唑阳离子（ICs）已被确认为一类具有强效抗肿瘤、抗菌和抗微生物特性的化学成分。所披露的咪唑阳离子对癌细胞表现出比当前临床标准顂铂更高或相等的效力。然而，这些咪唑阳离子在不引起类似顂铂等重金属抗肿瘤药物已知的毒副作用的情况下实现了这种功效。
• Ammonium redox-responsive receptors containing multiple ferrocene and quinone redox-active centres attached to di- and tri-aza crown ether macrocycles
  作者：Paul D. Beer、Declan B. Crowe、Mark I. Ogden、Michael G. B. Drew、Brian Main

  DOI：10.1039/dt9930002107

  日期：——

  ferrocene–ferrocenium redox couples of most of the ligands are perturbed to more positive potentials on co-ordination of NH4+ and K+ guest cations. The above tris(ferrocenylmethyl) ligand selectively binds and electrochemically recognises NH4+ in the presence of equimolar concentrations of K+. Secondary amide-linked ferrocene aza crown ether ligands electrochemically sense the NH4+ guest cation primarily via host ferrocenecarboxide

  已经制备了八种新的具有多个二茂铁和醌部分的氧化还原活性的二氮杂和三氮杂冠醚大环配体，包括第一个报道的二茂铁-醌混合大环配体。溶液1 H和13 C NMR络合研究表明，这些配体与铵作为客体阳离子形成1：1化学计量的络合物。7,16-双（二茂铁基甲基）-1,4,10,13-四氧杂-7,16-二氮杂环十八烷的六氟磷酸氢盐和4,10,16-三（二茂铁基甲基）-的铵络合物的单晶结构还确定了1,7,13-三恶唑-4,10,16-三氮杂环十八烷。电化学研究表明，大多数配体的各自的二茂铁-二茂铁氧化还原对在NH配位时被扰动到更正的电势4 +和K +客体阳离子。上述三（二茂铁）的配体选择性地结合和识别电化学NH 4 +中的K等摩尔浓度的存在+。二级酰胺连接的二茂铁氮杂冠醚配体主要通过主体二茂铁碳氧羰基氧-H-NH 3 +氢键静电相互作用电化学感应NH 4 +客体阳离子。
• Novel selective algaecides for control of cyanochloronta
  申请人：——

  公开号：US20040116536A1

  公开（公告）日：2004-06-17

  We have now discovered that certain 9,10-anthraquinone derivatives we developed possess potent activity against O. perornata while possessing a sufficiently high level of solubility in water to make their activity against O. perornata viable. These compounds possess a high level of activity against O. perornata yet are relatively non-toxic to green algae and fishes. The compounds also possess a relatively short half-life. The compounds represent a new means to providing compounds possessing a high degree of selective activity against blue-green algae while being physiologically tolerated by catfish and green algae. The compounds provide a means for controlling blue-green algae in managed bodies of water that are destined for public use or consumption.

  我们现在发现，我们开发的某些9,10-蒽醌衍生物具有对O. perornata的强效活性，同时具有足够高的水溶性，使它们对O. perornata的活性变得可行。这些化合物具有对O. perornata的高活性，但相对于绿藻和鱼类来说毒性较小。这些化合物也具有相对较短的半衰期。这些化合物代表了一种新的手段，提供了一种高度选择性对抗蓝藻的化合物，同时被鲶鱼和绿藻生理耐受。这些化合物提供了一种控制管理水体中蓝藻的手段，这些水体将用于公共使用或消费。
• Photoinduced electron transfer and charge separation in anthraquinone-substituted porphyrin–phthalocyanine heterodimer
  作者：Li Li、Shuyin Shen、Qun Yu、Qingfu Zhou、Huijun Xu

  DOI：10.1039/c39910000619

  日期：——

  Photoinduced intramolecular electron transfer in anthraquinone-substituted porphyrin–phthalocyanine heterodimer has been investigated by fluorescence quenching experiments and nanosecond flash photolysis techniques, giving a final charge separated state Zn(ttp)+˙–Zn(pc)–aq–(tpp = tetraphenyl porphyrin; pc = phthalocyanine; aq = anthraquine) dianion by exciting the phthalocyanine moiety.

  通过荧光淬灭实验和纳秒闪光光解技术对蒽醌取代卟啉-酞菁异二聚体中的光诱导分子内电子转移进行了研究，通过激发酞菁部分，最终得到电荷分离状态Zn(ttp)+⁺-Zn(pc)⁻-aq⁻（tpp = 四苯基卟啉；pc = 酞菁；aq = 蒽醌）二阴离子。
• Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods
  申请人：Wang Bing

  公开号：US20050113416A1

  公开（公告）日：2005-05-26

  Cytoprotective compounds, many of which are phenolic derivatives characterized by a substituted phenol having certain conjugated bonds, are useful in the treatment of certain ischemic or inflammatory conditions, including but not limited to stroke, myocardial infarction, congestive heart failure, and skin disorders characterized by inflammation or oxidative damage. They are also useful in the manufacture of pharmaceutical and cosmetic formulations for the treatment of such conditions.

  细胞保护化合物，其中许多是苯酚衍生物，其特征是具有特定共轭键的取代苯酚，对于治疗某些缺血或炎症状况非常有用，包括但不限于中风，心肌梗死，充血性心力衰竭以及皮肤疾病，其特征为炎症或氧化损伤。它们还可用于制造用于治疗这些疾病的药物和化妆品配方。