2-(3-hydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(3-hydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxylic acid
• 化学式: C₉H₁₄O₄
• 分子量: 186.2
• InChiKey: KWWDIBZCQVUVSH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF
  申请人：Ocata Therapeutics, Inc.

  公开号：EP2934555A1

  公开（公告）日：2015-10-28
• [EN] METHODS OFR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF<br/>[FR] PROCÉDÉS DE PRODUCTION DE PLAQUETTES À PARTIR DE CELLULES SOUCHES PLURIPOTENTES, ET COMPOSITIONS ASSOCIÉES
  申请人：ADVANCED CELL TECH INC

  公开号：WO2014100779A1

  公开（公告）日：2014-06-26

  Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.