7-[6-[[5-(4,5-Dihydroxy-6-methyloxan-2-yl)oxy-3-hydroxy-6-methyloxan-2-yl]oxymethyl]-4,5-dihydroxy-3-[4-hydroxy-5-[5-(4-hydroxy-5-methoxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3-hydroxydodecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-[6-[[5-(4,5-Dihydroxy-6-methyloxan-2-yl)oxy-3-hydroxy-6-methyloxan-2-yl]oxymethyl]-4,5-dihydroxy-3-[4-hydroxy-5-[5-(4-hydroxy-5-methoxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3-hydroxydodecanoic acid
• 英文别名: 7-[6-[[5-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-3-hydroxy-6-methyloxan-2-yl]oxymethyl]-4,5-dihydroxy-3-[4-hydroxy-5-[5-(4-hydroxy-5-methoxy-6-methyloxan-2-yl)oxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3-hydroxydodecanoic acid
• 化学式: C₄₉H₈₆O₂₃
• 分子量: 1043.2
• InChiKey: UOXCQLXXRIUQKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  72
• 可旋转键数：
  24
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.98
• 拓扑面积：
  319
• 氢给体数：
  9
• 氢受体数：
  23

文献信息

• NOVEL COMPOUND DERIVED FROM PLANT OF GENUS QUAMOCLIT AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING DIABETES
  申请人：KOREA RESEARCH INSTITUTE BIOSCIENCE

  公开号：US20160130293A1

  公开（公告）日：2016-05-12

  The present invention provides a novel compound isolated from a plant of the genus Quamoclit and a method for preparing a novel compound isolated from a plant of the genus Quamoclit through chemical synthesis, and relates to a novel compound and a composition containing the novel compound as an active ingredient for preventing or treating diabetes and diabetic complications. The compound derived from a plant of the genus Quamoclit and the composition containing the compound as an active ingredient according to the present invention have an excellent effect of promoting insulin secretion, thereby exhibiting efficacies in preventing or treating diabetes and the resulting various complications.

  本发明提供了一种从牵牛属植物中分离出的新化合物，以及通过化学合成制备从牵牛属植物中分离出的新化合物的方法，并涉及一种新化合物和含有该新化合物作为活性成分的组合物，用于预防或治疗糖尿病和糖尿病并发症。根据本发明从牵牛属植物中衍生的化合物和含有该化合物作为活性成分的组合物具有促进胰岛素分泌的优异效果，从而在预防或治疗糖尿病及其相关并发症方面表现出疗效。
• NOVEL COMPOUND ISOLATED FROM QUAMOCLIT, AND COMPOSITION FOR PREVENTING OR TREATING DIABETES CONTAINING THE COMPOUND AS AN ACTIVE INGREDIENT
  申请人：Chung Bong Hyun

  公开号：US20140179622A1

  公开（公告）日：2014-06-26

  The present invention relates to a novel compound isolated from Quamoclit sp., and more particularly to a novel compound isolated from Quamoclit sp. and a composition for preventing or treating diabetes and its complications comprising the compound as an active ingredient. The novel compound isolated from Quamoclit sp. according to the present invention has excellent effects on lowering blood sugar, promoting insulin secretion, inhibiting VEGF expression, and so on. Thus, the present invention not only functions to prevent or treat diabetes and its complications, but also functions to promote treatment effects when treated together with conventional diabetes medicines.
• US9487596B2
  申请人：——

  公开号：US9487596B2

  公开（公告）日：2016-11-08