methyl 1-[3-(2-hydroxypropoxy)-3-oxopropyl]-4-(N-propanoylanilino)piperidine-4-carboxylate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl 1-[3-(2-hydroxypropoxy)-3-oxopropyl]-4-(N-propanoylanilino)piperidine-4-carboxylate
• 化学式: C₂₂H₃₂N₂O₆
• 分子量: 420.5
• InChiKey: JXSDRBONXPAIDM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  30
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  96.4
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• STABLE LIQUID REMIFENTANIL FORMULATIONS
  申请人：MYLAN INC.

  公开号：US20140179740A1

  公开（公告）日：2014-06-26

  A stable, non-aqueous, liquid pharmaceutical composition contains remifentanil dissolved in a non-aqueous solvent. The formulation is provided with a pH ranging from about 2.0 to about 3.5 and can be used as an injectable. A method for preparing the formulation is also provided.
• [EN] STABLE LIQUID REMIFENTANIL FORMULATIONS<br/>[FR] FORMULATIONS LIQUIDES STABLES DE RÉMIFENTANIL
  申请人：MYLAN INC

  公开号：WO2014100624A1

  公开（公告）日：2014-06-26

  A stable, non-aqueous, liquid pharmaceutical composition contains remifentanil dissolved in a non-aqueous solvent. The formulation is provided with a pH ranging from about 2.0 to about 3.5 and can be used as an injectable. A method for preparing the formulation is also provided.