(2S)-2-(ethylamino)-4-methylpentanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-(ethylamino)-4-methylpentanamide
• 化学式: C₈H₁₈N₂O
• 分子量: 158.24
• InChiKey: HMAAHROABNSKDW-ZETCQYMHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• NOVEL GLP-1 RECEPTOR AGONISTS WITH CHOLESTEROL EFFLUX ACTIVITY
  申请人：NOVO NORDISK A/S

  公开号：US20150344540A1

  公开（公告）日：2015-12-03

  The present invention provides novel glucagon-like protein-1 (GLP-1) receptor agonist compounds that promote cholesterol efflux. The ABCA1-mediated cholesterol efflux present invention also provides compositions comprising the novel glucagon-like protein-1(GLP-1) receptor agonist compounds, and relates to the use of said compounds in therapy, to methods of treatment comprising administration of said compounds to patients, and to the use of said compounds in the manufacture of medicaments.
• [EN] NOVEL GLP-1 RECEPTOR AGONISTS WITH CHOLESTEROL EFFLUX ACTIVITY<br/>[FR] NOUVEAUX AGONISTES DES RÉCEPTEURS À LA GLP-1 AVEC ACTIVITÉ D'EFFLUX DU CHOLESTÉROL
  申请人：NOVO NORDISK AS

  公开号：WO2014096179A1

  公开（公告）日：2014-06-26

  The present invention provides novel glucagon-like protein-1(GLP-1) receptor agonist compounds that promote cholesterol efflux. The present invention also provides compositions comprising the novel glucagon-like protein-1(GLP-1) receptor agonist compounds, and relates to the use of said compounds in therapy, to methods of treatment comprising administration of said compounds to patients, and to the use of said compounds in the manufacture of medicaments.