2-aminohexanedioic acid;(2S)-2,6-diaminohexanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-aminohexanedioic acid;(2S)-2,6-diaminohexanoic acid
• 化学式: C12H25N3O6
• 分子量: 307.34
• InChiKey: IIIDMSHNJIEMRO-JEDNCBNOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.82
• 重原子数：
  21
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  190
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CARBON CHAIN ELONGATION ASSOCIATED WITH CYCLOHEXANE CARBOXYLATE SYNTHESIS
  申请人：Invista Technologies S.A R.L.

  公开号：EP2938731A2

  公开（公告）日：2015-11-04
• Methods Of Producing 7-Carbon Chemicals Via Carbon Chain Elongation Associated With Cyclohexane Carboxylate Synthesis
  申请人：INVISTA North America S.á r.I.

  公开号：US20140193862A1

  公开（公告）日：2014-07-10

  This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the carbon chain elongation enzymes or homologs thereof associated with the cyclohexane carboxylate biosynthesis from Syntrophus aciditrophicus or 2-aminoadipate lysine biosynthesis.
• US9637764B2
  申请人：——

  公开号：US9637764B2

  公开（公告）日：2017-05-02
• [EN] METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CARBON CHAIN ELONGATION ASSOCIATED WITH CYCLOHEXANE CARBOXYLATE SYNTHESIS<br/>[FR] PROCÉDÉS DE PRODUCTION D'AGENTS CHIMIQUES À 7 ATOMES DE CARBONE PAR ALLONGEMENT DE CHAÎNE CARBONE ASSOCIÉ À LA SYNTHÈSE DE CYCLOHEXANE CARBOXYLATE
  申请人：INVISTA NORTH AMERICA SARL

  公开号：WO2014105788A2

  公开（公告）日：2014-07-03

  This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the carbon chain elongation enzymes or homologs thereof associated with the cyclohexane carboxylate biosynthesis from Syntrophus aciditrophicus or 2-aminoadipate lysine biosynthesis.