2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;methyl 2-hydroxybenzoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;methyl 2-hydroxybenzoate
• 化学式: C22H30N2O4
• 分子量: 386.5
• InChiKey: QPDIOIVAVNFNPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.76
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  78.9
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• BODY SURFACE TREATMENT COMPOSITION AND METHOD
  申请人：Arms Pharmaceutical LLC.

  公开号：EP2941248A1

  公开（公告）日：2015-11-11
• [EN] BODY SURFACE TREATMENT COMPOSITION AND METHOD<br/>[FR] COMPOSITION ET PROCÉDÉ DE TRAITEMENT DE SURFACE CORPORELLE
  申请人：ARMS PHARMACEUTICAL LLC

  公开号：WO2014107572A1

  公开（公告）日：2014-07-10

  A method for treating a body surface with an active agent, includes: administering a composition in a therapeutically effective amount to a body surface, the composition forming a barrier coating on the body surface that is active to sustain contact with the body surface for a duration of at least about one hour. The composition meets the following requirements: about 0.0001% < C < about 0.4%, about 0.07% < H < about 70%, optionally an antimicrobial A, and a therapeutically effective amount of X; or 0%< C < about 0.4%, about 55% < H < about 70%, optionally an antimicrobial A, and a therapeutically effective amount of X. All percentages are by weight of the total composition and C is a carbohydrate gum; H is a humectant; and A is the active agent, the active agent being active to produce a therapeutic effect on the body.