2-(Difluoromethylidene)-3,3,4,4,5,5,6,6,7,7-decafluorooctanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-(Difluoromethylidene)-3,3,4,4,5,5,6,6,7,7-decafluorooctanoic acid
• 英文别名: 2-(difluoromethylidene)-3,3,4,4,5,5,6,6,7,7-decafluorooctanoic acid
• 化学式: C₉H₄F₁₂O₂
• 分子量: 372.11
• InChiKey: UCQKDLXXYRGOJA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  14

文献信息

• MEDICAL DEVICE, COMBINATION OF COATING SOLUTIONS, AND METHOD FOR PRODUCING MEDICAL DEVICE
  申请人：Nakamura Masataka

  公开号：US20140198294A1

  公开（公告）日：2014-07-17

  Disclosed is a medical device having an elastic modulus of 100 kPa or more and 2,000 kPa or less, a water content of 10% by mass or less, a tensile elongation of 50% or more and 3,000% or less, and a dynamic contact angle (advancing angle) relative to a borate buffer of 80° or less. The present invention can significantly reduce or avoid a phenomenon of adhesion to a surface when contacted with a surface outside or inside the body, which has hitherto been regarded as a problem in a conventional medical device.

  本发明公开了一种医疗器械，其弹性模量为100 kPa或更高，2,000 kPa或更低，水含量为质量的10%或更低，拉伸延伸率为50%或更高，3,000%或更低，相对于硼酸缓冲液的动态接触角（前进角）为80°或更低。本发明可以显著减少或避免与体内外表面接触时粘附的现象，这在传统医疗器械中一直被视为问题。
• Medical device, combination of coating solutions, and method for producing medical device
  申请人：Nakamura Masataka

  公开号：US10591749B2

  公开（公告）日：2020-03-17

  Disclosed is a medical device having an elastic modulus of 100 kPa or more and 2,000 kPa or less, a water content of 10% by mass or less, a tensile elongation of 50% or more and 3,000% or less, and a dynamic contact angle (advancing angle) relative to a borate buffer of 80° or less. The present invention can significantly reduce or avoid a phenomenon of adhesion to a surface when contacted with a surface outside or inside the body, which has hitherto been regarded as a problem in a conventional medical device.

  本发明公开了一种医疗器械，其弹性模量为 100 kPa 或以上、2,000 kPa 或以下，含水量为 10%（质量分数）或以下，拉伸伸长率为 50%或以上、3,000% 或以下，相对于硼酸盐缓冲液的动态接触角（推进角）为 80°或以下。本发明可显著减少或避免与体外或体内表面接触时的表面粘附现象，而这种现象在传统医疗器械中一直被视为一个问题。
• US9046644B2
  申请人：——

  公开号：US9046644B2

  公开（公告）日：2015-06-02
• US9377562B2
  申请人：——

  公开号：US9377562B2

  公开（公告）日：2016-06-28