5-O-amino 1-O-methyl pentanedioate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-O-amino 1-O-methyl pentanedioate
• 化学式: C₆H₁₁NO₄
• 分子量: 161.16
• InChiKey: LWSHQTLMTAIRAV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  78.6
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• METHOD FOR PRODUCING DESMOSINE, ISODESMOSINE AND DERIVATIVES THEREOF
  申请人：Sophia School Corporation

  公开号：EP2952504B1

  公开（公告）日：2017-10-11
• TARGETING VECTOR-PHOSPHOLIPID CONJUGATES
  申请人：Bussat Philippe

  公开号：US20080107607A1

  公开（公告）日：2008-05-08

  Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic methods, such as in imaging KDR-containing tissue and in the evaluation and treatment of angiogenic processes associated with neoplastic conditions. The present invention also provides processes for the large scale production of highly pure dimeric and monomeric peptide phospholipid conjugates as well as precursor materials used to form the conjugates. The present invention further provides processes for the large scale production of highly pure peptide phospholipid conjugates which contain very low levels of TFA.
• US9295737B2
  申请人：——

  公开号：US9295737B2

  公开（公告）日：2016-03-29
• US9381258B2
  申请人：——

  公开号：US9381258B2

  公开（公告）日：2016-07-05