(2E,4E)-2-cyano-5-[ethyl(2-hydroxyethyl)amino]penta-2,4-dienoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2E,4E)-2-cyano-5-[ethyl(2-hydroxyethyl)amino]penta-2,4-dienoic acid
• 化学式: C₁₀H₁₄N₂O₃
• 分子量: 210.23
• InChiKey: AHVNBPXQSCQVOR-BMVOEDMYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  84.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] USE OF A REINFORCED ANTI-SUN PROTECTION COMPOSITION IN PROTECTION AGAINST LONG UVA RAYS FOR PROTECTING ONESELF AGAINST HERPES ATTACKS INDUCED BY EXPOSURE TO THE SUN<br/>[FR] UTILISATION D'UNE COMPOSITION DE PROTECTION SOLAIRE RENFORCÉE DANS LA PROTECTION CONTRE LES RAYONS UVA LONGS POUR SE PROTÉGER CONTRE DES ATTAQUES D'HERPÈS INDUITES L'EXPOSITION AU SOLEIL
  申请人：OREAL

  公开号：WO2014111588A2

  公开（公告）日：2014-07-24

  The invention relates to a cosmetic or dermatological composition comprising, in a physiologically acceptable support, at least one merocyanine compound for preventing reactivation of the herpes simplex virus (HSV) type 1 and/or an outbreak of herpes attacks and/or the occurrence of skin disorders induced by said reactivation and/or said outbreak. It also relates to a method of screening, in vitro or ex vivo,for active agents capable of limiting and/or of inhibiting the modulation of expression of at least one ofthe genes chosen from IFIT1, IFIT2, TLR3, DDX58 or CXCL10.