(2,5-Dioxopyrrolidin-1-yl) 4-morpholin-4-ylsulfonylheptan-2-yl carbonate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: (2,5-Dioxopyrrolidin-1-yl) 4-morpholin-4-ylsulfonylheptan-2-yl carbonate
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 4-morpholin-4-ylsulfonylheptan-2-yl carbonate
• 化学式: C₁₆H₂₆N₂O₈S
• 分子量: 406.5
• InChiKey: FYJQBLAGQYQOGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  128
• 氢给体数：
  0
• 氢受体数：
  9

文献信息

• SEALANTS HAVING CONTROLLED DEGRADATION
  申请人：Prolynx LLC

  公开号：EP2925256A1

  公开（公告）日：2015-10-07
• [EN] SEALANTS HAVING CONTROLLED DEGRADATION<br/>[FR] PRODUITS D'ÉTANCHÉITÉ AYANT UNE DÉGRADATION CONTRÔLÉE
  申请人：PROLYNX LLC

  公开号：WO2014116717A1

  公开（公告）日：2014-07-31

  The invention provides sealants wherein biodegradable hydrogels that do not otherwise comprise protein-reactive groups for binding to membranes or tissue are provided said groups optionally through a linker. The linker may be biodegradable and may be biodegradable by an elimination reaction. The invention also provides multilayer gels for drug delivery wherein a porous gel in contact with a tissue or organ to which the drug is to be delivered is protected by a microporous layer from the surrounding bodily fluid.