N-[[4-(hydroxymethyl)-4-methylcyclohexa-1,5-dien-1-yl]-phenylmethyl]-2-phenoxyacetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-[[4-(hydroxymethyl)-4-methylcyclohexa-1,5-dien-1-yl]-phenylmethyl]-2-phenoxyacetamide
• 化学式: C₂₃H₂₅NO₃
• 分子量: 363.4
• InChiKey: PXZMBOWVISQBNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  27
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  58.6
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• TETRAZINES/TRANS-CYCLOOCTENES IN SOLID PHASE SYNTHESIS OF LABELED PEPTIDES
  申请人：Memorial Sloan-Kettering Cancer Center

  公开号：EP2948186A1

  公开（公告）日：2015-12-02
• PEPTIDES FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH ADIPONECTIN DYSFUNCTION
  申请人：AUCKLAND UNISERVICES LIMITED

  公开号：US20200223894A1

  公开（公告）日：2020-07-16

  The present invention provides peptides comprising a cargo peptide and a cell penetrating peptide that bind ERp44, peptides comprising a cargo peptide and a cell penetrating peptide that increase secretion of adiponectin from cells and methods of treating or preventing diseases associated with adiponectin dysfunction by administering said peptides.
• [EN] TETRAZINES/TRANS-CYCLOOCTENES IN SOLID PHASE SYNTHESIS OF LABELED PEPTIDES<br/>[FR] TÉTRAZINES/TRANS-CYCLOOCTÈNES DANS LA SYNTHÈSE EN PHASE SOLIDE DE PEPTIDES MARQUÉS
  申请人：SLOAN KETTERING INST CANCER

  公开号：WO2014117001A1

  公开（公告）日：2014-07-31

  This invention is in the field of labeled peptide construction for medical treatment and analysis. The invention relates to synthetic labeled peptide compositions, methods of synthesis, and methods of use for the synthetic labeled peptide compositions for medical treatment, imaging, and research purposes.