3-[(12S)-12-(4-aminobutyl)-5-[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]-15-[3-(diaminomethylideneamino)propyl]-17-methyl-2,7,10,13,16-pentaoxo-1,3,5,8,11,14,17-heptazacyclohenicos-9-yl]propanamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 3-[(12S)-12-(4-aminobutyl)-5-[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]-15-[3-(diaminomethylideneamino)propyl]-17-methyl-2,7,10,13,16-pentaoxo-1,3,5,8,11,14,17-heptazacyclohenicos-9-yl]propanamide
• 化学式: C₃₇H₆₀N₁₄O₇
• 分子量: 813.0
• InChiKey: MIGZTFDJLOXCEJ-KZJCOHJUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  58
• 可旋转键数：
  14
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  344
• 氢给体数：
  11
• 氢受体数：
  10

文献信息

• COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE
  申请人：The Regents of the University of Michigan

  公开号：US20140212444A1

  公开（公告）日：2014-07-31

  The present invention provides compositions and methods for inducing an immune response in a subject. In particular, the present invention provides compositions comprising immunostimulatory ligands (ISL) and methods of inducing an immune response in a subject therewith. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
• US9555086B2
  申请人：——

  公开号：US9555086B2

  公开（公告）日：2017-01-31