(Z)-N-hexacosan-13-ylicos-9-enamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (Z)-N-hexacosan-13-ylicos-9-enamide
• 化学式: C₄₆H₉₁NO
• 分子量: 674.2
• InChiKey: BGSIGVLDMYHJAD-QPLCGJKRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  21
• 重原子数：
  48
• 可旋转键数：
  41
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• SUBSTANTIALLY DRY NICOTINAMIDE PADS FOR TREATMENT OF SKIN INFLAMMATION
  申请人：Sanyal Bharat Janardan

  公开号：US20140220101A1

  公开（公告）日：2014-08-07

  A substantially dry nonwoven pad is provided containing a formulation comprising nicotinamide in an amount between about 1% to about 10% w/w based on the total weight of the formulation and at least one water-soluble gritty polymer in an amount between about 10% to about 75% w/w based on the total weight of the formulation. The nicotinamide-containing pad is used topically for treatment of skin inflammation, in one easy step. In a method for treating skin inflammation, including acne, rosacea, and acne scars (hyperpigmentation), the nicotinamide-containing pad is moistened, then applied to the skin treatment area using gentle scrubbing, followed by rapid absorption of the formulation by the skin, and rinsing the skin with water.