(3S)-4-amino-3-[[2-[[(2S)-2-aminopropanoyl]amino]acetyl]amino]-4-oxobutanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (3S)-4-amino-3-[[2-[[(2S)-2-aminopropanoyl]amino]acetyl]amino]-4-oxobutanoic acid
• 化学式: C₉H₁₆N₄O₅
• 分子量: 260.25
• InChiKey: ZXWCKWQKQZRVEZ-WHFBIAKZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.4
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  165
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• Biodegradable Iron Oxide Nanoparticle Gel for Tumor Bed Therapy
  申请人：The Trustees of Dartmouth College

  公开号：US20140219926A1

  公开（公告）日：2014-08-07

  A biodegradable iron oxide nanoparticle gel for hyperthermia treatment of cancer includes a polysaccharide-based carrier matrix and starch-coated iron oxide nanoparticles. The gel has sufficient deformability to integrate into a diffuse tumor site, adheres to tissue and has sufficient mechanical properties to remain in place during hyperthermia treatment. The gel releases iron oxide nanoparticles for uptake by cancerous cells at the tumor margin.