US9144538, Glutamylamidoethyl

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: US9144538, Glutamylamidoethyl
• 英文别名: (4S)-4-amino-5-[1-(1H-imidazol-2-yl)ethylamino]-5-oxopentanoic acid
• 化学式: C₁₀H₁₆N₄O₃
• 分子量: 240.26
• InChiKey: VDKVZHLKFOQAKN-MLWJPKLSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  121
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR IMPROVING THE APPEARANCE OF AGING SKIN
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：US20140227206A1

  公开（公告）日：2014-08-14

  Methods of improving the appearance of aging skin that include applying a cosmetic composition to a target skin surface having one or more signs of aging. The cosmetic composition includes a substituted azole. In some instances, the substituted azole compound is 1-phenylimidazole, 4-phenylimidazole, or combinations thereof. An effective amount of the cosmetic composition is applied for a period of time sufficient to improve the appearance of at least one sign of aging skin.
• COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN
  申请人：The Procter & Gamble Company

  公开号：US20140227207A1

  公开（公告）日：2014-08-14

  Cosmetic compositions for alleviating the signs of photoaged skin containing a substituted azole. Methods for alleviating the signs of photoaged skin that include applying a cosmetic composition comprising substituted azole to a target UV-exposed skin surface. The substituted azole compound present in the cosmetic composition may be 1-phenylimidazole, 4-phenylimidazole or a combination thereof. An effective amount of the cosmetic composition is applied to the target skin surface for a period of time sufficient to alleviate at least one sign of photoaging.
• COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING MECHANICALLY-INDUCED SKIN INFLAMMATION
  申请人：The Procter & Gamble Company

  公开号：US20140227208A1

  公开（公告）日：2014-08-14

  Compositions for alleviating mechanically-induced skin inflammation, such as that caused by shaving, contain substituted azole. Methods for alleviating mechanically-induced skin inflammation include the step of applying a composition comprising substituted azole to a skin surface subject to mechanically-induced inflammation. In particular embodiments the substituted azole compound is 1-phenylimidazole, 4-phenylimidazole, or a combination thereof. An effective amount of the composition is applied for a period of time sufficient to alleviate mechanically-induced skin inflammation.
• US9138393B2
  申请人：——

  公开号：US9138393B2

  公开（公告）日：2015-09-22
• US9144538B2
  申请人：——

  公开号：US9144538B2

  公开（公告）日：2015-09-29