(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;(2S)-pyrrolidine-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;(2S)-pyrrolidine-2-carboxylic acid
• 化学式: C16H32N6O6
• 分子量: 404.46
• InChiKey: SFCSNLNISUQNHX-MOBQZEGBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  226
• 氢给体数：
  8
• 氢受体数：
  10

文献信息

• Method for the diagnosis of or risk for a disease mediated via the alternative pathway of the complement system
  申请人：Eberhard Karls Universitaet Tuebingen Medizinische Fakultaet

  公开号：US10416173B2

  公开（公告）日：2019-09-17

  The present invention relates to a method for the diagnosis of a disease or a risk for the development of a disease, in particular a disease which is mediated via the alternative pathway of the complement system. It further relates to a novel diagnostic marker and methods for identifying active agents.

  本发明涉及一种诊断疾病或疾病发展风险的方法，特别是通过补体系统替代途径介导的疾病。本发明还涉及一种新型诊断标记物和识别活性剂的方法。
• PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF
  申请人：Tel HaShomer Medical Research Infrastructure and Services Ltd.

  公开号：EP2953978A1

  公开（公告）日：2015-12-16
• VERFAHREN ZUR DIAGNOSE EINER DURCH DEN ALTERNATIVEN WEG DES KOMPLEMENTSYSTEMS VERMITTELTEN KRANKHEIT ODER EINES RISIKOS HIERFÜR
  申请人：Eberhard Karls Universität Tübingen Medizinische Fakultät

  公开号：EP3149485B1

  公开（公告）日：2021-03-03
• METHOD FOR THE DIAGNOSIS OF OR RISK FOR A DISEASE MEDIATED VIA THE ALTERNATIVE PATHWAY OF THE COMPLEMENT SYSTEM
  申请人：Eberhard Karls Universitaet Tuebingen Medizinische Fakultaet

  公开号：US20170160291A1

  公开（公告）日：2017-06-08

  The present invention relates to a method for the diagnosis of a disease or a risk for the development of a disease, in particular a disease which is mediated via the alternative pathway of the complement system. It further relates to a novel diagnostic marker and methods for identifying active agents.
• US9533030B2
  申请人：——

  公开号：US9533030B2

  公开（公告）日：2017-01-03