H-Ser(1)-OH.H-Lys-(1).H-Arg-OH.H-Pro-OH

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: H-Ser(1)-OH.H-Lys-(1).H-Arg-OH.H-Pro-OH
• 英文别名: (2S)-2-amino-3-[(2S)-2,6-diaminohexanoyl]oxypropanoic acid;(2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;(2S)-pyrrolidine-2-carboxylic acid
• 化学式: C20H42N8O8
• 分子量: 522.6
• InChiKey: FWBMFUAHNWWWGM-BJVICJANSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.33
• 重原子数：
  36
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  319
• 氢给体数：
  10
• 氢受体数：
  14

文献信息

• PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF
  申请人：Tel HaShomer Medical Research Infrastructure and Services Ltd.

  公开号：EP2953978A1

  公开（公告）日：2015-12-16
• Phosphorylcholine Conjugates and Uses Thereof
  申请人：TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTD.

  公开号：US20160193350A1

  公开（公告）日：2016-07-07

  The present invention provides phosphorylcholine (PC)-conjugates and pharmaceutical compositions, particularly vaccines comprising same for the prevention or treatment of autoimmune diseases. In particular, the PC-conjugates of the present invention are effective in preventing or treating autoimmune diseases associated with pathological inflammation.
• US9987372B2
  申请人：——

  公开号：US9987372B2

  公开（公告）日：2018-06-05
• [EN] PHOSPHORYLCHOLINE CONJUGATES AND USES THEREOF<br/>[FR] CONJUGÉS DE PHOSPHORYLCHOLINE ET LEURS UTILISATIONS
  申请人：TEL HASHOMER MEDICAL RES INFRASTRUCTURE & SERVICES LTD

  公开号：WO2014122646A1

  公开（公告）日：2014-08-14

  The present invention provides phosphorylcholine (PC)-conjugates and pharmaceutical compositions, particularly vaccines comprising same for the prevention or treatment of autoimmune diseases. In particular, the PC-conjugates of the present invention are effective in preventing or treating autoimmune diseases associated with pathological inflammation.