(2S)-2-[[(4S)-5-methyl-2-[2-(2-methyl-1,3-oxazol-4-yl)-1,3-oxazol-4-yl]-4,5-dihydro-1,3-oxazole-4-carbonyl]amino]-3-phenylpropanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-[[(4S)-5-methyl-2-[2-(2-methyl-1,3-oxazol-4-yl)-1,3-oxazol-4-yl]-4,5-dihydro-1,3-oxazole-4-carbonyl]amino]-3-phenylpropanoic acid
• 化学式: C₂₁H₂₀N₄O₆
• 分子量: 424.4
• InChiKey: LTWXJOJQDQDEPE-ULQHUPADSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  140
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• ANTIBIOTICS AND METHODS FOR MANUFACTURING THE SAME
  申请人：THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

  公开号：US20140228278A1

  公开（公告）日：2014-08-14

  The present invention generally relates to a novel highly discriminating antibiotic, plantazolicin, a plantazolicin-like compound and to pharmaceutical compositions comprising the same. Also provided are methods for producing and using plantazolicin. Due to its bactericidal activity against Bacillus anthracis , plantazolicin and plantazolicin-like compounds can be used in methods for treating and/or preventing anthrax infections.