Methyl-4-isopropoxybutyrat | 29006-05-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Methyl-4-isopropoxybutyrat
• 英文别名: Methyl 4-isopropoxybutanoate；methyl 4-propan-2-yloxybutanoate
• CAS: 29006-05-1
• 化学式: C₈H₁₆O₃
• 分子量: 160.213
• InChiKey: NOVXZKWAELINSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  Methyl propan-2-yl butanedioate 、 三氯硅烷 生成 Methyl-4-isopropoxybutyrat
  参考文献：
  名称：

  OKA, KUNIO;NAKAO, REN;FUKUMOTO, TSUGIO, ANNU. REPT RAIDAT. CENT. OSAKA PREFECT., 1982, 23, 55-60

  摘要：

  DOI：

文献信息

• Mass spectrometry in structural and stereochemical problems. CCII. Interaction of remote functional groups in acyclic systems upon electron impact
  作者：Carl Djerassi、Michael Sheehan、Richard J. Spangler、M. Ikeda

  DOI：10.1021/jo00812a017

  日期：1971.7
• METHODS AND COMPOSITIONS FOR THE TREATMENT OF BCR-ABL POSITIVE LYMPHOBLASTIC LEUKEMIAS
  申请人：ST. JUDE CHILDREN'S RESEARCH HOSPITAL

  公开号：US20150133462A1

  公开（公告）日：2015-05-14

  In one aspect, the invention relates to compositions comprising BCR-ABL tyrosine kinase inhibitors and artemisinin analogues, derivatives thereof, or related compounds, which are useful as in treating Philadelphia chromosome positive leukemias; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with BCR-ABL dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• US9801851B2
  申请人：——

  公开号：US9801851B2

  公开（公告）日：2017-10-31
• OKA, KUNIO;NAKAO, REN;FUKUMOTO, TSUGIO, ANNU. REPT RAIDAT. CENT. OSAKA PREFECT., 1982, 23, 55-60
  作者：OKA, KUNIO、NAKAO, REN、FUKUMOTO, TSUGIO

  DOI：——

  日期：——