(2S)-2-amino-3-[3-(1,3,4-thiadiazol-2-yl)phenyl]propanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-amino-3-[3-(1,3,4-thiadiazol-2-yl)phenyl]propanoic acid
• 化学式: C₁₁H₁₁N₃O₂S
• 分子量: 249.29
• InChiKey: GGCGJIHSXBVVNR-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Cathepsin-binding compounds bound to a carrier and their diagnostic use
  申请人：J. Stefan Institute

  公开号：US10668175B2

  公开（公告）日：2020-06-02

  The invention relates to Cathepsin-binding compounds bound to a carrier comprising a diagnostic moiety, for use in the diagnosis of inflammatory diseases, and/or for use in the diagnosis of neoplastic diseases, wherein the Cathepsin-binding compound binds to inflammatory cells of the tumour stroma. The invention also relates to Cathepsin B-targeting compounds and Cathepsin B-binding and liposome-binding compounds.

  本发明涉及与包含诊断分子的载体结合的钙蛋白结合化合物，用于诊断炎症性疾病和/或用于诊断肿瘤性疾病，其中钙蛋白结合化合物与肿瘤基质的炎症细胞结合。本发明还涉及鲶鱼蛋白酶 B 靶向化合物和鲶鱼蛋白酶 B 结合及脂质体结合化合物。
• CATHEPSIN-BINDING COMPOUNDS BOUND TO A CARRIER AND THEIR DIAGNOSTIC USE
  申请人：Vasiljeva Olga

  公开号：US20140227175A1

  公开（公告）日：2014-08-14

  The invention relates to Cathepsin-binding compounds bound to a carrier comprising a diagnostic moiety, for use in the diagnosis of inflammatory diseases, and/or for use in the diagnosis of neoplastic diseases, wherein the Cathepsin-binding compound binds to inflammatory cells of the tumour stroma. The invention also relates to Cathepsin B-targeting compounds and Cathepsin B-binding and liposome-binding compounds.
• US9827337B2
  申请人：——

  公开号：US9827337B2

  公开（公告）日：2017-11-28