Calcium;cyclopentanecarboxylate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Calcium;cyclopentanecarboxylate
• 英文别名: calcium;cyclopentanecarboxylate
• 化学式: C12H18CaO4
• 分子量: 266.35
• InChiKey: DHVHATLXXFBSKR-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -0.53
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Topical compositions and methods of using the same
  申请人：Novan, Inc.

  公开号：US10258564B2

  公开（公告）日：2019-04-16

  The present invention relates generally to compositions and methods of using the same. A first aspect of the present invention comprises a composition comprising a first viscosity increasing agent; at least one polyhydric alcohol; at least one buffering agent; at least one preservative; a second viscosity increasing agent; at least one organic solvent; at least one humectant; at least one active pharmaceutical ingredient; and water, wherein the composition is buffered to a pH of about 3 to about 11.

  本发明一般涉及组合物及其使用方法。本发明的第一个方面包括一种组合物，该组合物包含第一增粘剂；至少一种多羟基乙醇；至少一种缓冲剂；至少一种防腐剂；第二增粘剂；至少一种有机溶剂；至少一种保湿剂；至少一种活性药物成分；以及水，其中该组合物的缓冲 pH 值约为 3 至约 11。
• Topical antiviral compositions and methods of using the same
  申请人：Novan, Inc.

  公开号：US10322081B2

  公开（公告）日：2019-06-18

  The present invention relates generally to topical antiviral compositions and methods of using the same.

  本发明一般涉及局部抗病毒组合物及其使用方法。
• Electrochemical gasotransmitter generating compositions and methods of using same and dressings and treatment systems incorporating same
  申请人：Noxsano Inc.

  公开号：US10342706B2

  公开（公告）日：2019-07-09

  Disclosed are compositions that comprise an organic electrochemical mediator and a gasotransmitter salt which converts into a gasotransmitter via electron transfer. Also disclosed are bandages and wound dressings comprising the subject gasotransmitters, and methods of making a gasotransmitters, comprising exposing the compositions to a voltage sufficient to reduce the water soluble organic mediator. Further disclosed are methods of treating a variety of trauma and disease states by applying a therapeutically effective amount of at least one gasotransmitter thereto, and methods of generating an effective dose of the gasotransmitter generated from electrolytic reaction involving the gasotransmitter-generating compositions.

  本发明公开了由有机电化学介质和气体传递盐组成的组合物，气体传递盐通过电子转移转化为气体传递剂。还公开了包含上述气体传递剂的绷带和伤口敷料，以及制造气体传递剂的方法，包括将组合物置于足以降低水溶性有机介质的电压下。进一步公开的是通过在创伤和疾病状态下施用治疗有效量的至少一种气体递质来治疗各种创伤和疾病的方法，以及通过涉及产生气体递质的组合物的电解反应产生有效剂量的气体递质的方法。
• Topical antiviral compositions, delivery systems, and methods of using the same
  申请人：Novan, Inc.

  公开号：US10736839B2

  公开（公告）日：2020-08-11

  The present invention relates generally to topical antiviral compositions, delivery systems, and methods of using the same.

  本发明一般涉及局部抗病毒组合物、给药系统和使用方法。
• Compositions for treating inflammation and methods of treating the same
  申请人：Novan, Inc.

  公开号：US10912743B2

  公开（公告）日：2021-02-09

  Provided herein are compositions useful for treating inflammation in a subject and methods of decreasing inflammation in the skin, mucosa, and/or eye of a subject comprising applying a pharmaceutical composition that includes an NO-releasing compound to the skin, mucosa, and/or eye of the subject in an amount sufficient to decrease inflammation.

  本文提供了用于治疗受试者炎症的组合物，以及减轻受试者皮肤、粘膜和/或眼部炎症的方法，该方法包括向受试者的皮肤、粘膜和/或眼部施用药物组合物，该药物组合物包括一种释放 NO 的化合物，施用量足以减轻炎症。