2-methyl-2-(1H-pyrrol-3-yl)butanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 2-methyl-2-(1H-pyrrol-3-yl)butanamide
• 化学式: C₉H₁₄N₂O
• 分子量: 166.22
• InChiKey: PAUNUIUHRQZHAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：EP2958897A2

  公开（公告）日：2015-12-30
• [EN] COMPOUNDS USEFUL AS MODULATORS OF TRPM8<br/>[FR] COMPOSÉS UTILES COMME MODULATEURS DE TRPM8
  申请人：SENOMYX INC

  公开号：WO2014130582A2

  公开（公告）日：2014-08-28

  The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.