[(3S,4S,6R)-3,4,5-trimethyl-6-[(2S,4S,5S)-3,4,5-trimethyl-6-(3-undecyltetradecanoyloxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl 3-undecyltetradecanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: [(3S,4S,6R)-3,4,5-trimethyl-6-[(2S,4S,5S)-3,4,5-trimethyl-6-(3-undecyltetradecanoyloxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl 3-undecyltetradecanoate
• 化学式: C₆₈H₁₃₀O₇
• 分子量: 1059.8
• InChiKey: ISIIXGUEPMGTPU-ZFNVBDTESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  28.5
• 重原子数：
  75
• 可旋转键数：
  52
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  80.3
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• TREHALOSE COMPOUND, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL PRODUCT CONTAINING THE COMPOUND
  申请人：GLYTECH, INC.

  公开号：US20140248317A1

  公开（公告）日：2014-09-04

  A trehalose compound having high immunopotentiating activity and low toxicity is represented by formula (1). (In the formula, X and X′ each represents a phenyl, a naphthyl, R 1 —CHR 1 — (wherein R 1 and R 2 each represents a C 7 -C 21 alkyl group or the like) or the like; and n and n′ each independently represents an integer of 0-3). The compound exhibits a high activating effect on macrophages and neutrophils.

  具有高免疫增强活性和低毒性的海藻糖类化合物由式（1）表示。（在公式中，X和X'分别表示苯基，萘基，R1-CHR1-（其中R1和R2各表示C7-C21烷基或类似物）或类似物; n和n'各自独立表示0-3的整数）。该化合物表现出对巨噬细胞和中性粒细胞的高活化效应。