(4E)-4-(dimethylaminomethylidene)-2-(4-methylphenyl)-1,3-oxazol-5-one

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (4E)-4-(dimethylaminomethylidene)-2-(4-methylphenyl)-1,3-oxazol-5-one
• 化学式: C₁₃H₁₄N₂O₂
• 分子量: 230.26
• InChiKey: CFEDQSBXLMNVQP-DHZHZOJOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Azlactone compound and method for preparation thereof
  申请人：Ajinomoto Co., Inc.

  公开号：EP1533306A1

  公开（公告）日：2005-05-25

  The present invention provides a preparation method of a compound represented by the formula (II): wherein M is a hydrogen atom, sodium, potassium or lithium, P is a hydrogen atom, an alkyl group and the like and a wavy line shows a cis form, a trans form or a mixture thereof for the carbon-carbon double bond to which it is attached, which includes hydrolyzing a compound represented by the formula (I): wherein R1 and R2 are the same or different and each is an alkyl group, or may form an aliphatic heterocycle together with the adjacent nitrogen atom, and P and a wavy line are as defined above, or a salt thereof, in the presence of alkali metal hydroxide.

  本发明提供了一种由以下化合物代表的化合物的制备方法（II）：其中M是氢原子、钠、钾或锂，P是氢原子、烷基基团等，波浪线表示其连接的碳-碳双键的顺式形式、反式形式或它们的混合物，包括在碱金属氢氧化物存在下水解由以下式表示的化合物（I）：其中R1和R2相同或不同，每个是烷基基团，或者与相邻氮原子一起形成脂环杂环，P和波浪线如上所定义，或其盐。
• AZLACTONE COMPOUND AND METHOD FOR PREPARATION THEREOF
  申请人：TAKAHASHI Daisuke

  公开号：US20080188667A1

  公开（公告）日：2008-08-07

  Compounds represented by formula (II): wherein M is a hydrogen atom, sodium, potassium, or lithium; P is a hydrogen atom, an alkyl group, and the like; and the wavy line indicates a cis form, a trans form, or a mixture thereof for the double bond to which it is attached, may be prepared by hydrolyzing a compound represented by formula (I), or a salt thereof: wherein R 1 and R 2 are the same or different and each is an alkyl group, or R 1 and R 2 together with the adjacent nitrogen atom may form an aliphatic heterocycle, and P and the wavy line are as defined above, in the presence of alkali metal hydroxide.
• US7358368B2
  申请人：——

  公开号：US7358368B2

  公开（公告）日：2008-04-15