5-[[2,4,4,6,6-Pentakis(3,5-diformylphenoxy)-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-trien-2-yl]oxy]benzene-1,3-dicarbaldehyde | 926317-26-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-[[2,4,4,6,6-Pentakis(3,5-diformylphenoxy)-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-trien-2-yl]oxy]benzene-1,3-dicarbaldehyde
• 英文别名: 5-[[2,4,4,6,6-pentakis(3,5-diformylphenoxy)-1,3,5-triaza-2λ5,4λ5,6λ5-triphosphacyclohexa-1,3,5-trien-2-yl]oxy]benzene-1,3-dicarbaldehyde
• CAS: 926317-26-2
• 化学式: C₄₈H₃₀N₃O₁₈P₃
• 分子量: 1029.7
• InChiKey: AJGUJEKPJYIWMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  72
• 可旋转键数：
  24
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  297
• 氢给体数：
  0
• 氢受体数：
  21

反应信息

• 作为反应物：
  描述：

  5-[[2,4,4,6,6-Pentakis(3,5-diformylphenoxy)-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-trien-2-yl]oxy]benzene-1,3-dicarbaldehyde 、 dichloro(1-methylhydrazido)thiophosphane 以 氯仿 为溶剂， 以77%的产率得到
  参考文献：
  名称：

  Reduced number of steps for the synthesis of dense and highly functionalized dendrimers

  摘要：

  A series of densely functionalized dendrimers is synthesized using two branched monomers of type AB(2) and CD2, in which the A function (NH2) reacts with D (CHO) and the B function (Cl) reacts with C (OH). The reaction has been carried out up to the fourth generation possessing 96 end groups and has been obtained ill only four steps. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.11.112
• 作为产物：
  描述：

  3,5-二(羟甲基)苯酚 在 manganese(IV) oxide 、 Na₃P₃Cl₆ 、 sodium hydride 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 96.0h， 生成 5-[[2,4,4,6,6-Pentakis(3,5-diformylphenoxy)-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-trien-2-yl]oxy]benzene-1,3-dicarbaldehyde
  参考文献：
  名称：

  Reduced number of steps for the synthesis of dense and highly functionalized dendrimers

  摘要：

  A series of densely functionalized dendrimers is synthesized using two branched monomers of type AB(2) and CD2, in which the A function (NH2) reacts with D (CHO) and the B function (Cl) reacts with C (OH). The reaction has been carried out up to the fourth generation possessing 96 end groups and has been obtained ill only four steps. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.11.112

文献信息

• Crown Macromolecular Derivatives: Stepwise Design of New Types of Polyfunctionalized Phosphorus Dendrimers
  作者：Andrii Karpus、Serge Mignani、Maria Zablocka、Jean Pierre Majoral

  DOI：10.1021/acs.joc.1c03009

  日期：2022.3.4

  to diversify their structure in order to use them for new applications and to propose alternative synthetic pathways to be built easily, at each step and in high yield a family of original stable phosphorus dendrimers of different generations. Such a goal is illustrated in this report with the original synthesis of 14 new phosphorus dendrimers of generation 0 to 2 and the possibility to modify at will

  磷树枝状大分子用于不同领域的许多应用，包括纳米医学作为药物货物或作为本身具有活性的物种而且在从纳米科学到催化的各种其他领域。它们的性质取决于其内部结构的性质，主要取决于位于其外壳上的官能团的多样性和多功能性。因此，需要使它们的结构多样化，以便将它们用于新的应用，并提出可以在每个步骤中轻松构建的替代合成途径，并以高产率构建不同代的原始稳定磷树枝状大分子家族。这一目标在本报告中阐明，最初合成了 0 至 2 代的 14 种新的磷树枝状大分子，并且可以随意修改它们的内部结构和末端官能团的性质。
• Reduced number of steps for the synthesis of dense and highly functionalized dendrimers
  作者：Paul Servin、Cyrille Rebout、Régis Laurent、Maurizio Peruzzini、Anne-Marie Caminade、Jean-Pierre Majoral

  DOI：10.1016/j.tetlet.2006.11.112

  日期：2007.1

  A series of densely functionalized dendrimers is synthesized using two branched monomers of type AB(2) and CD2, in which the A function (NH2) reacts with D (CHO) and the B function (Cl) reacts with C (OH). The reaction has been carried out up to the fourth generation possessing 96 end groups and has been obtained ill only four steps. (c) 2006 Elsevier Ltd. All rights reserved.