(2S)-2,6-diaminohexanoic acid;3-nonyloxepan-2-one

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2,6-diaminohexanoic acid;3-nonyloxepan-2-one
• 化学式: C21H42N2O4
• 分子量: 386.6
• InChiKey: UEZGXMRBIWCQMK-ZSCHJXSPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.0
• 重原子数：
  27
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  116
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• XANTHINE OXIDASE INHIBITOR FORMULATIONS
  申请人：Allen, Davidoff

  公开号：EP3001814A2

  公开（公告）日：2016-04-06
• [EN] XANTHINE OXIDASE INHIBITOR FORMULATIONS<br/>[FR] FORMULATIONS D'INHIBITEUR DE XANTHINE OXYDASE
  申请人：ALLEN DAVIDOFF

  公开号：WO2014140868A2

  公开（公告）日：2014-09-18

  Disclosed herein are methods and compositions for involving a xanthine oxidase inhibitor that has enhanced solubility. The compositions described herein include a xanthine oxidase inhibitor combined with an organic base. The compositions can be used to treat a disease or medical condition that involves elevated uric acid levels.
• [EN] METHODS OF TREATING VIRAL INFECTIONS AND HEALTH CONSEQUENCES<br/>[FR] PROCÉDÉS DE TRAITEMENT D'INFECTIONS VIRALES ET DES CONSÉQUENCES SUR LA SANTÉ
  申请人：DAVIDOFF ALLEN

  公开号：WO2021186250A2

  公开（公告）日：2021-09-23

  This invention relates to formulations of uric acid lowering agent(s) (UALA) designed to inhibit xanthine oxidase and/or decrease serum or tissue uric acid concentration for the treatment and prevention of morbidities and mortality during viral infection. For example, acute kidney injury due to coronavirus infection by administering a therapeutically effective amount of an agent capable of inhibiting xanthine oxidase and/or decreasing uric acid levels in a patient in need of such treatment. Additionally, the scope of the invention includes a method of treating and preventing acute kidney injury and health consequences due to coronavirus infection.