5-amino-3-(1H-imidazol-5-yl)-2-(octanoylamino)-4-oxohexanoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5-amino-3-(1H-imidazol-5-yl)-2-(octanoylamino)-4-oxohexanoic acid
• 化学式: C₁₇H₂₈N₄O₄
• 分子量: 352.4
• InChiKey: KCBWNGBVWCZQAC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  25
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  138
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME
  申请人：Neocutis SA

  公开号：EP2970382A2

  公开（公告）日：2016-01-20
• [EN] PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME<br/>[FR] PEPTIDES POUR LE RAJEUNISSEMENT DE LA PEAU ET LEURS PROCÉDÉS D'UTILISATION
  申请人：NEOCUTIS SA

  公开号：WO2014140890A2

  公开（公告）日：2014-09-18

  The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and/or tetrapeptides as well as pharmaceutical and/or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and/or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components.