2,3-diaminopropanoyl (2S)-2,3-diaminobutanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,3-diaminopropanoyl (2S)-2,3-diaminobutanoate
• 化学式: C₇H₁₆N₄O₃
• 分子量: 204.23
• InChiKey: LSYPBIANDNRUQZ-YCXLAJEKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.3
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  147
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• GENERATION OF ACYL AMINO ACIDS
  申请人：Modular Genetics, Inc.

  公开号：EP2970928A1

  公开（公告）日：2016-01-20
• [EN] GENERATION OF ACYL AMINO ACIDS<br/>[FR] PRODUCTION D'ACIDES AMINÉS ACYLÉS
  申请人：MODULAR GENETICS INC

  公开号：WO2014144649A1

  公开（公告）日：2014-09-18

  In certain embodiments, the present invention comprises compositions and methods useful in the generation of acyl amino acids. In certain embodiments, the present invention provides an engineered polypeptide comprising a peptide synthetase domain; in some such embodiments, the engineered polypeptide comprises only a single peptide synthetase domain. In some embodiments, the present invention provides an engineered peptide synthetase that is substantially free of a thioesterase domain, and/or a reductase domain. In certain embodiments, the present invention provides an acyl amino acid composition comprising a plurality of different forms of an acyl amino acid. In some such compositions, substantially all of the acyl amino acids within the composition contain the same amino acid moiety and differ with respect to acyl moiety. We also described populations where the fatty acid si for example 95% one length (C14, myristic).