[EN] PEPTIDES COMPRISING NON-NATURAL AMINO ACIDS AND METHODS OF MAKING AND USING THE SAME<br/>[FR] PEPTIDES COMPRENANT DES ACIDES AMINÉS NON ENDOGÈNES ET PROCÉDÉS DE FABRICATION ET D'UTILISATION ASSOCIÉS
申请人:LONGEVITY BIOTECH INC
公开号:WO2014145718A2
公开(公告)日:2014-09-18
This invention relates to novel compositions comprising analogs of naturally occurring polypeptides, wherein the analog comprises an α-amino acid and at least one β-amino acid. Administration of the compositions may be used for effecting treatment or prevention of a plurality of disease states caused by dysfunctional biochemical or biological pathways. The compositions and methods of this invention are particularly useful to identify novel therapeutic modulators of in-vivo receptor activity with extended half-lives and relevant bioactivity as compared to the naturally translated polypeptides upon which the analogs are derived.