N-[(E,2S,3R)-1-[bromo(2-bromoethoxy)phosphoryl]oxy-3-hydroxyoctadec-4-en-2-yl]hexadecanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-[(E,2S,3R)-1-[bromo(2-bromoethoxy)phosphoryl]oxy-3-hydroxyoctadec-4-en-2-yl]hexadecanamide
• 化学式: C₃₆H₇₀Br₂NO₅P
• 分子量: 787.7
• InChiKey: WIVMBZRNOFYEDF-KRZQJUTLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  14.5
• 重原子数：
  45
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  84.9
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS
  申请人：CERENIS THERAPEUTICS HOLDING SA

  公开号：US20140316154A1

  公开（公告）日：2014-10-23

  The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.

  本发明涉及合成鞘磷脂和二氢鞘磷脂的方法。本发明还涉及合成鞘氨醇和二氢鞘氨醇的方法。本发明还涉及合成鞘醇和二氢鞘醇的方法。
• US9643915B2
  申请人：——

  公开号：US9643915B2

  公开（公告）日：2017-05-09
• [EN] METHODS FOR THE SYNTHESIS OF SPHINGOMYELINS AND DIHYDROSPHINGOMYELINS<br/>[FR] PROCÉDÉS POUR LA SYNTHÈSE DE SPHINGOMYÉLINES ET DE DIHYDROSPHINGOMYÉLINES
  申请人：CERENIS THERAPEUTICS HOLDING SA

  公开号：WO2014140787A2

  公开（公告）日：2014-09-18

  The present invention includes methods for the synthesis of sphingomyelins and dihydrosphingomyelins. The present invention also includes methods for the synthesis of sphingosines and dihydrosphingosines. The present invention further includes methods for the synthesis of ceramides and dihydroceramides.