1-O-[2-(dimethylamino)ethyl] 5-O-(2-methoxyethyl) 2-bromo-2,4,4-trimethylpentanedioate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 1-O-[2-(dimethylamino)ethyl] 5-O-(2-methoxyethyl) 2-bromo-2,4,4-trimethylpentanedioate
• 化学式: C₁₅H₂₈BrNO₅
• 分子量: 382.29
• InChiKey: VEMAOHPNDLSHMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  22
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  65.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• US20140275420A1
  申请人：——

  公开号：US20140275420A1

  公开（公告）日：2014-09-18
• ATOM TRANSFER RADICAL POLYMERIZATION UNDER BIOLOGICALLY COMPATIBLE CONDITIONS
  申请人：Carnegie Mellon University

  公开号：US20170145048A1

  公开（公告）日：2017-05-25

  Methods for conducting controlled grafting-from radical polymerizations from biomolecules under conditions that are biologically compatible are described. The methods provide biomolecule-polymer conjugates with highly controlled structures and narrow polydispersities under aqueous reaction conditions and biological temperatures. Biomolecules, such as proteins and nucleotides can be conjugated to polymers with high levels of control.