3-[3-[[[2-(2-Carboxy-4,5-dihydroxy-6-propan-2-yloxyoxan-3-yl)oxy-5-hydroxy-6-(hydroxymethyl)-4-propan-2-yloxyoxan-3-yl]amino]methylamino]-5-hydroxy-6-(hydroxymethyl)-4-propan-2-yloxyoxan-2-yl]oxy-4,5-dihydroxy-6-propan-2-yloxyoxane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3-[3-[[[2-(2-Carboxy-4,5-dihydroxy-6-propan-2-yloxyoxan-3-yl)oxy-5-hydroxy-6-(hydroxymethyl)-4-propan-2-yloxyoxan-3-yl]amino]methylamino]-5-hydroxy-6-(hydroxymethyl)-4-propan-2-yloxyoxan-2-yl]oxy-4,5-dihydroxy-6-propan-2-yloxyoxane-2-carboxylic acid
• 英文别名: 3-[3-[[[2-(2-carboxy-4,5-dihydroxy-6-propan-2-yloxyoxan-3-yl)oxy-5-hydroxy-6-(hydroxymethyl)-4-propan-2-yloxyoxan-3-yl]amino]methylamino]-5-hydroxy-6-(hydroxymethyl)-4-propan-2-yloxyoxan-2-yl]oxy-4,5-dihydroxy-6-propan-2-yloxyoxane-2-carboxylic acid
• 化学式: C₃₇H₆₆N₂O₂₂
• 分子量: 890.9
• InChiKey: VDYKEUNGZXZRDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.8
• 重原子数：
  61
• 可旋转键数：
  20
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  353
• 氢给体数：
  12
• 氢受体数：
  24

文献信息

• US20140274941A1
  申请人：——

  公开号：US20140274941A1

  公开（公告）日：2014-09-18
• Hyaluronic Acid Derivatives
  申请人：Anacoti Ltd.

  公开号：US20180051100A1

  公开（公告）日：2018-02-22

  The present disclosure relates to hyaluronic acid derivatives, and in particular, derivatives in which the N-acetyl group of hyaluronic acid has been substituted, and methods and uses thereof.