4-(dimethylamino)-N-[(9Z,28Z,31Z)-octatriaconta-9,28,31-trien-19-yl]butanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-(dimethylamino)-N-[(9Z,28Z,31Z)-octatriaconta-9,28,31-trien-19-yl]butanamide
• 化学式: C₄₄H₈₄N₂O
• 分子量: 657.1
• InChiKey: FXROAQQSJMINDZ-RWLIYIGXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.7
• 重原子数：
  47
• 可旋转键数：
  37
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PROCESS FOR FORMULATING AN ANIONIC AGENT
  申请人：Dicerna Pharmaceuticals, Inc.

  公开号：EP2968149A1

  公开（公告）日：2016-01-20
• [EN] PROCESS FOR FORMULATING AN ANIONIC AGENT<br/>[FR] PROCÉDÉ DE FORMULATION D'UN AGENT ANIONIQUE
  申请人：DICERNA PHARMACEUTICALS INC

  公开号：WO2014153163A1

  公开（公告）日：2014-09-25

  Formulations comprising anionic agents such as nucleic acids within a lipid-containing particle methods of formulating a lipid-containing particle comprising an anionic agent such as a nucleic acid, methods for preparing a lipid-containing particle comprising an anionic agent such as a nucleic acid, methods for therapeutic delivery of an anionic agent to a patient in need thereof, where the anionic agent is formulated in a lipid-containng particle as described herein.