6-Diphenylphosphanyl-2-methylidenehexanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-Diphenylphosphanyl-2-methylidenehexanoic acid
• 英文别名: 6-diphenylphosphanyl-2-methylidenehexanoic acid
• 化学式: C₁₉H₂₁O₂P
• 分子量: 312.3
• InChiKey: NTORVFNSGCUHTM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  22
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• COMPOSITIONS, METHODS AND DEVICES FOR PROMOTING WOUND HEALING AND REDUCING INFECTION
  申请人：Iasis Molecular Sciences

  公开号：EP2967076A2

  公开（公告）日：2016-01-20
• [EN] COMPOSITIONS, METHODS AND DEVICES FOR PROMOTING WOUND HEALING AND REDUCING INFECTION<br/>[FR] COMPOSITIONS, PROCÉDÉS ET DISPOSITIFS DESTINÉS À FAVORISER LA CICATRISATION DE PLAIE ET À RÉDUIRE LES INFECTIONS
  申请人：IASIS MOLECULAR SCIENCES

  公开号：WO2014153238A2

  公开（公告）日：2014-09-25

  Compositions, methods and devices are provided for promoting healing and preventing and treating infection in mammalian subjects. The compositions include pharmacologically active, protease inhibiting, cytokine protecting, aqueous media soluble sulfonated materials, optionally associated with one or more secondary therapeutic agents or carriers, to reduce one or more of inflammation, bacterial proliferation and proteolytic activity. Additionally provided are solubility increasing, stability increasing, toxicity decreasing thiol compounds associated with an antimicrobial compound and optionally secondary therapeutic agents to reduce one or more of inflammation and bacterial infection. Combinations of sulfonated and thiol compounds provide pharmacologically active, protease inhibiting, cytokine protecting, aqueous media soluble, antibacterial, stable, toxicity decreasing, solubility increasing compounds for treating wounds, including burns, in humans and other mammals.