6-(Hexadecyloxy)-6-oxohexanoic acid | 10108-00-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-(Hexadecyloxy)-6-oxohexanoic acid
• 英文别名: 6-hexadecoxy-6-oxohexanoic acid
• CAS: 10108-00-6
• 化学式: C₂₂H₄₂O₄
• 分子量: 370.6
• InChiKey: BPOSRHRZGSYVSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  26
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes
  申请人：McDaniel C. Steven

  公开号：US20100210745A1

  公开（公告）日：2010-08-19

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peotide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文公开了一些聚合材料，如涂层、塑料、层压板、复合材料、弹性体、粘合剂或密封剂；一种表面处理，如纺织品涂层或蜡；一种填料，用于这样的聚合材料或表面处理，其中包括一种酶，如酯酶（例如，脂肪水解酶，硫酸酯水解酶，有机磷化合物降解酶），降解细胞壁和/或细胞膜成分的酶（例如，溶菌酶，裂解转糖基酶），生物杀菌或生物静态肽，以及/或肽酶。本文还公开了通过将酶纳入可通过脂肪水解酶、水解酶和/或脲酶的活性交联材料中来改变材料性能，如使用寿命、柔韧性或刚度的方法。
• Anti-fouling Paints and Coatings
  申请人：Reactive Surfaces LTD

  公开号：US20150191607A1

  公开（公告）日：2015-07-09

  Disclosed herein are polymeric materials such as a coating, a plastic, a laminate, a composite, an elastomer, an adhesive, or a sealant; a surface treatment such as a textile finish or a wax; a filler for such a polymeric material or a surface treatment that includes an enzyme such as an esterase (e.g., a lipolytic enzyme, a sulfuric ester hydrolase, an organophosphorus compound degradation enzyme), an enzyme (e.g., a lysozyme, a lytic transglycosylase) that degrades a cell wall and/or a cell membrane component, a biocidal or biostatic peptide, and/or a peptidase. Also disclosed herein are methods of altering a material's property such as service life, flexability, or rigidity, by incorporation of an enzyme into a material capable of being chemically crosslinked by the activity of a lipolytic enzyme, a hydrolase, and/or a urease.

  本文披露了聚合材料，例如涂层、塑料、层压材料、复合材料、弹性体、粘合剂或密封剂；表面处理，例如纺织品整理或蜡；填充剂，用于这种聚合材料或表面处理，包括酯酶（例如脂肪水解酶、硫酸酯水解酶、有机磷化合物降解酶）的酶，降解细胞壁和/或细胞膜成分的酶（例如溶菌酶、裂解转葡糖苷酶），生物杀菌或生物稳定肽，和/或肽酶。本文还披露了通过将酶并入能够通过脂肪水解酶、水解酶和/或脲酶的活性进行化学交联的材料中，改变材料性能（例如使用寿命、柔韧性或刚度）的方法。
• Rhizoxin derivates and their use as anti-tumor agents
  申请人：SANKYO COMPANY LIMITED

  公开号：EP0350315A1

  公开（公告）日：1990-01-10

  Rhizoxin and rhizoxin-2-ene derivatives of formula (I): [in which: n is 1 to 25; A is an extra bond or oxygen, X is oxygen, sulphur, nitrogen or carbonyl; and R is hydrogen, carboxylic acyl having from 1 to 25 carbon atoms, alkoxycarbonyl group having from 2 to 26 carbon atoms, phosphono, alkylphosphono group in which the alkyl part has from 1 to 25 carbon atoms, dialkyl­phosphono group in which each alkyl part has from 1 to 25 carbon atoms, alkyl group having from 1 to 25 carbon atoms, aralkyl, cycloalkyl, heterocyclic, alkylthio group in which the alkyl part has from 1 to 25 carbon atoms, aralkylthio, or heterocyclylthio, or when X represents a nitrogen atom, R is R¹ and R², where R¹ and R² are hydrogen, alkyl, acyl, alkoxycarbonyl, phosphono, alkylphosphono or dialkylphosphono] have valuable anti-tumour activity. They may be prepared by acylation of rhizoxin or rhizoxin-2-ene.

  式(I)的根肿灵和根肿灵-2-烯衍生物： 其中n 为 1 至 25；A 为额外键或氧，X 为氧、硫、氮或羰基；和 R 是氢、具有 1 至 25 个碳原子的羧酰基、具有 2 至 26 个碳原子的烷氧羰基、膦酰基、烷基膦酰基（其中烷基部分具有 1 至 25 个碳原子）、二烷基膦酰基（其中每个烷基部分具有 1 至 25 个碳原子）、具有 1 至 25 个碳原子的烷基、或当 X 代表氮原子时，R 为 R¹ 和 R²，其中 R¹ 和 R²为氢、烷基、酰基、烷氧羰基、膦酰基、烷基膦酰基或二烷基膦酰基]具有重要的抗肿瘤活性。它们可通过 rhizoxin 或 rhizoxin-2-ene 的酰化反应制备。
• Water-in-oil type cosmetic emulsion containing amide derivatives
  申请人：KAO CORPORATION

  公开号：EP0842655A2

  公开（公告）日：1998-05-20

  Described is a water-in-oil type cosmetic emulsion comprising (A) an amide compound having a melting point of 0 to 50°C and (B) a nonionic surfactant having an HLB smaller than 8. The cosmetic composition according to the present invention has excellent stability, can enhance the water-retaining ability of the stratum corneum and has excellent skin-roughness lessening effects.

  本发明描述了一种油包水型化妆品乳液，它包含(A)熔点为 0 至 50°C 的酰胺化合物和(B)HLB 小于 8 的非离子表面活性剂。
• Acrylic polymer composition for cosmetics
  申请人：National Starch and Chemical Investment Holding Corporation

  公开号：EP1486514A1

  公开（公告）日：2004-12-15

  The invention provides a resin for cosmetics with superior transparency that yields excellent balance between properties such as water resistance, adhesion, lasting effect and pulling feel. The resin for cosmetics is a resin for cosmetics obtained by emulsion polymerization of a monomer mixture containing: (A): at least one selected from the group consisting of acrylic acid, methacrylic acid, maleic acid, itaconic acid and crotonic acid, (B): at least one selected from the group consisting of alkyl(meth)acrylate monomers having an alkyl group with a carbon number of 1 to 4, and (C): at least one selected from the group consisting of alkyl(meth)acrylate monomers having an alkyl group with a carbon number of 5 or more, wherein the monomer mixture contains 10 to 20 parts by weight of the (A), 40 to 80 parts by weight of the (B) and 10 to 40 parts by weight of the (C), based upon the total of the (A) to (C) taken as 100 parts by weight.

  本发明提供了一种透明性极佳的化妆品用树脂，可在耐水性、粘附性、持久效果和拉扯感等特性之间取得极佳的平衡。该化妆品用树脂是通过乳液聚合单体混合物获得的化妆品用树脂，该单体混合物包含：(A)：至少一种选自丙烯酸、甲基丙烯酸、马来酸、衣康酸和巴豆酸的单体；(B)：至少一种选自具有碳原子数为 1 至 4 的烷基的烷基（甲基）丙烯酸酯单体；以及(C)：从具有碳数为 5 或更多烷基的烷基（甲基）丙烯酸酯单体组成的组中选出的至少一种单体，其中单体混合物含有 10 至 20 份（按重量计）(A)、40 至 80 份（按重量计）(B)和 10 至 40 份（按重量计）(C)，以(A)至(C)的总和为 100 份（按重量计）为基准。