diclofop | 71283-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diclofop
• 英文别名: (2R)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoic acid
• CAS: 71283-28-8
• 化学式: C₁₅H₁₂Cl₂O₄
• 分子量: 327.164
• InChiKey: OOLBCHYXZDXLDS-SECBINFHSA-N

物化性质

• 沸点：
  440.5±45.0 °C(Predicted)
• 密度：
  1.386±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  diclofop 生成 (2R)-2-[4-(2,4-二氯苯氧基)苯氧基]丙酸甲酯
  参考文献：
  名称：

  HERBRECHTSMEIER, P.;KOCH, M.

  摘要：

  DOI：
• 作为产物：
  描述：

  4-(2,4-二氯苯氧基)苯酚 在 sodium hydroxide 、 potassium carbonate 作用下， 以 甲醇 、 丙酮 为溶剂， 反应 22.5h， 生成 diclofop
  参考文献：
  名称：

  Nestler, Hans Juergen; Bieringer, Hermann, Zeitschrift fur Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, 1980, vol. 35, # 3, p. 366 - 371

  摘要：

  DOI：

文献信息

• Process for producing optically active 2-phenoxypropionic acid
  申请人：Kirin Beer Kabushiki Kaisha

  公开号：US04803301A1

  公开（公告）日：1989-02-07

  There is provided a process for producing an optically active 2-phenoxypropionic acid, which comprises allowing an optically active lactic ester represented by the following formula (I) to react with a phenol represented by the following formula (II) in the copresence of a reagent A and a reagent B defined below to form an optically active 2-phenoxypropionic ester represented by the following formula (III), and liberating an optically active 2-phenoxypropionic acid represented by the following formula (IV) from the optically active 2-phenoxypropionic ester: ##STR1## wherein R.sup.1 represents a group to form a monovalent ester, which can be eliminated from the compound (III) under weakly basic to acidic conditions and R.sup.2 represents a hydrogen atom or 1 to 5 substituents which do not interfere in the reaction between the compounds (I) and (II); a reagent A being at least one compound selected from the group consisting of trialkylphosphine, trialkylphosphite, triarylphosphine and triarylphosphite; and a reagent B being at least one compound selected from the group consisting of dialkylazodicarboxylate and diarylazodicarboxylate.

  提供一种生产光学活性2-苯氧基丙酸的方法，包括允许以下式(I)所代表的光学活性乳酸酯与以下式(II)所代表的苯酚在下述定义的试剂A和试剂B的共存下反应，形成以下式(III)所代表的光学活性2-苯氧基丙酸酯，并从光学活性2-苯氧基丙酸酯中释放出以下式(IV)所代表的光学活性2-苯氧基丙酸：其中R.sup.1代表形成一价酯的基团，可以在弱碱性至酸性条件下从化合物(III)中消除，R.sup.2代表氢原子或在化合物(I)和(II)之间的反应中不干扰的1至5个取代基；试剂A至少是从三烷基膦、三烷基膦酸酯、三芳基膦和三芳基膦酸酯组成的群体中选择的至少一种化合物；试剂B至少是从二烷基偶氮二羧酸酯和二芳基偶氮二羧酸酯组成的群体中选择的至少一种化合物。
• Nanocellulose Derivative/Silica Hybrid Core-Shell Chiral Stationary Phase: Preparation and Enantioseparation Performance
  作者：Xiaoli Zhang、Litao Wang、Shuqing Dong、Xia Zhang、Qi Wu、Liang Zhao、Yanping Shi

  DOI：10.3390/molecules21050561

  日期：——

  Core-shell silica microspheres with a nanocellulose derivative in the hybrid shell were successfully prepared as a chiral stationary phase by a layer-by-layer self-assembly method. The hybrid shell assembled on the silica core was formed using a surfactant as template by the copolymerization reaction of tetraethyl orthosilicate and the nanocellulose derivative bearing triethoxysilyl and 3,5-dimethylphenyl groups. The resulting nanocellulose hybrid core-shell chiral packing materials (CPMs) were characterized and packed into columns, and their enantioseparation performance was evaluated by high performance liquid chromatography. The results showed that CPMs exhibited uniform surface morphology and core-shell structures. Various types of chiral compounds were efficiently separated under normal and reversed phase mode. Moreover, chloroform and tetrahydrofuran as mobile phase additives could obviously improve the resolution during the chiral separation processes. CPMs still have good chiral separation property when eluted with solvent systems with a high content of tetrahydrofuran and chloroform, which proved the high solvent resistance of this new material.

  通过逐层自组装方法，成功制备了在混合壳中具有纳米纤维素衍生物的核壳硅微球作为手性固定相。在硅核上组装的混合壳是通过表面活性剂作为模板，通过正硅酸四乙酯与带有三乙氧基硅烷基和3,5-二甲基苯基的纳米纤维素衍生物的共聚反应形成的。对所得的纳米纤维素混合核壳手性填料（CPMs）进行了表征并装入色谱柱，通过高效液相色谱法评估了其手性分离性能。结果表明，CPMs具有均匀的表面形貌和核壳结构。在正相和反相模式下，各种类型的手性化合物均被有效地分离。此外，作为流动相添加剂的氯仿和四氢呋喃可以明显提高手性分离过程中的分辨率。当用四氢呋喃和氯仿含量高的溶剂体系洗脱时，CPMs仍然具有良好的手性分离性能，这证明了这种新材料具有很高的耐溶剂性。
• USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS
  申请人：Rosinger Christopher

  公开号：US20080269052A1

  公开（公告）日：2008-10-30

  According to the invention, compounds of the general formula (I) or salts thereof (pyridine-2-oxy-3-carboxamides), in which R 1 is a (C 1 -C 4 )-haloalkyl radical can be employed as safeners, i.e. as agents for preventing or reducing phytotoxic effects of pesticides, preferably herbicides, on useful plants.

  根据这项发明，通式（I）的化合物或其盐（吡啪酮-2-氧基-3-羧酰胺），其中R1是（C1-C4）卤代烷基基团，可用作安全剂，即用于防止或减轻杀虫剂，特别是除草剂对有用植物的毒害作用的药剂。
• A covalent organic framework for chiral capillary electrochromatography using a cyclodextrin mobile phase additive
  作者：Lidi Gao、Xuan Zhao、Shili Qin、Qing Dong、Xingfang Hu、Hongtao Chu

  DOI：10.1002/chir.23405

  日期：2022.3

  about 6.00 μm for the column prepared under the optimal conditions. Enantioseparation of 15 kinds of the single chiral compounds (histidine, arginine, lysine, leucine, threonine, methionine, valine, aspartic acid and glutamic acid, fipronil, diclofop, imazamox, quizalofop-p, imazethapyr, and acephate) and 3 kinds of mixed amino acids racemaces (valine, methionine, and glutamic acid) were performed with

  共价有机框架 (COF) 已被认为是毛细管电色谱 (CEC) 中很有前途的固相。制备了亚胺基COF涂层开管CEC柱（COF TpBD涂层OT柱），并通过X射线衍射（XRD）、傅里叶变换红外（FT-IR）光谱、热重分析（TGA）、氮气吸附/解吸（Brunauer-Emmett-Teller [BET]）和扫描电子显微镜（SEM）。结果表明，在最佳条件下制备的色谱柱柱效可达26776板/米，固定相厚度约为6.00 μm。15种单一手性化合物（组氨酸、精氨酸、赖氨酸、亮氨酸、苏氨酸、蛋氨酸、缬氨酸、天冬氨酸和谷氨酸、氟虫腈、双氯氟草胺、咪草啶酸、喹唑啉磷、咪草烟、采用COF TpBD包被的OT柱毛细管电色谱法（方法1）和COF TpBD包被的OT柱作为CEC的三种方法对3种混合氨基酸外消旋体（缬氨酸、蛋氨酸和谷氨酸）进行分析。分离通道，以及以 HP-β-CD 作为手性流动相添加剂的毛细管电泳 (CE)（方法
• Herbicidal method comprising the use of diflufenican
  申请人：MAY & BAKER LIMITED

  公开号：EP0255272A1

  公开（公告）日：1988-02-03

  The present invention relates to a method of controlling the growth of weeds at a cereal crop locus which comprises applying to the locus (a) diclofop, which is (R,S)-2[4-(2,4. dichlorophenoxyjphenoxy]-propionic acid or an agriculturally acceptable salt or esterthereof and (b) diflufenican which is N-(2,4-difluorophenyl)-2-(3-trifluoromethylphenoxy)-nicotinamide.

  本发明涉及一种控制谷类作物基因座上杂草生长的方法，它包括向基因座施用(a)双氟磺草胺，即(R,S)-2[4-(2,4.二氯苯氧基)-丙酸或其农业上可接受的盐或酯和(b)双氟吡草胺，即N-(2,4-二氟苯基)-2-(3-三氟甲基苯氧基)-烟酰胺。