2-hydroxy-N-[2-hydroxy-3-[4-(N'-hydroxycarbamimidoyl)-3-methylphenoxy]propyl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2-hydroxy-N-[2-hydroxy-3-[4-(N'-hydroxycarbamimidoyl)-3-methylphenoxy]propyl]acetamide
• 化学式: C₁₃H₁₉N₃O₅
• 分子量: 297.31
• InChiKey: BURJFMWMDUQULP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  21
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  137
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• NOVEL PYRIMIDINE DERIVATIVES
  申请人：Bolli Martin

  公开号：US20100234346A1

  公开（公告）日：2010-09-16

  The invention relates to novel pyrimidine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. Formula (I) wherein A represents Formula (II), Formula (III), Formula (IV), Formula (V), Formula (VI), Formula (VII), Formula (VIII) or Formula (IX)

  这项发明涉及新型嘧啶衍生物，它们的制备以及它们作为药用活性化合物的用途。这些化合物特别作为免疫调节剂。公式（I）其中A代表公式（II）、公式（III）、公式（IV）、公式（V）、公式（VI）、公式（VII）、公式（VIII）或公式（IX）。
• THIOPHENE DERIVATIVES AS AGONISTS OF S1P1/EDG1
  申请人：Bolli Martin

  公开号：US20100261702A1

  公开（公告）日：2010-10-14

  The invention relates to novel thiophene derivatives (1), their preparation and their use as pharmaceutically active compounds.Said compounds particularly act as immunomodulating agents. Formula (I).

  这项发明涉及新型噻吩衍生物（1），它们的制备以及它们作为药用活性化合物的用途。这些化合物特别作为免疫调节剂。公式（I）。
• [EN] PYRIDINE COMPOUNDS<br/>[FR] COMPOSÉS DE PYRIDINE
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2009109906A1

  公开（公告）日：2009-09-11

  The invention relates to pyridine compounds, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

  这项发明涉及吡啶化合物，它们的制备以及它们作为药用活性化合物的用途。这些化合物特别作为免疫调节剂。
• PYRIDINE COMPOUNDS
  申请人：Bolli Martin

  公开号：US20110028448A1

  公开（公告）日：2011-02-03

  The invention relates to pyridine compounds, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

  该发明涉及吡啶化合物，其制备和用作药物活性化合物。这些化合物特别作为免疫调节剂。
• NOVEL AMINOMETHYL BENZENE DERIVATIVES
  申请人：Bolli Martin

  公开号：US20110028449A1

  公开（公告）日：2011-02-03

  The invention relates to novel aminomethyl benzene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.

  本发明涉及新型氨甲基苯衍生物，其制备和作为药物活性化合物的用途。所述化合物特别作用为免疫调节剂。