4-[2-[[5-(2-Fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]-1,3-dihydroquinoxalin-2-one

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-[2-[[5-(2-Fluoroanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]acetyl]-1,3-dihydroquinoxalin-2-one
• 化学式: C₁₈H₁₄FN₅O₂S₂
• 分子量: 415.5
• InChiKey: PCYAUWNTIQGGNX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  141
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• INTERFERON-INDUCING COMPOUNDS AND USES THEREOF
  申请人：Shaw Megan

  公开号：US20120308608A1

  公开（公告）日：2012-12-06

  Provided herein are Compounds that induce interferon production and methods for identifying such Compounds. Also provided herein are compositions comprising such Compounds and methods of using such Compounds to treat interferon-sensitive diseases such as viral infections, cancer, and multiple sclerosis.
• [EN] INTERFERON-INDUCING COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS INDUISANT L'INTERFÉRON ET LEURS UTILISATIONS
  申请人：SINAI SCHOOL MEDICINE

  公开号：WO2011094693A1

  公开（公告）日：2011-08-04

  Provided herein are Compounds that induce interferon production and methods for identifying such Compounds. Also provided herein are compositions comprising such Compounds and methods of using such Compounds to treat interferon-sensitive diseases such as viral infections, cancer, and multiple sclerosis.