6-(3-氯丙氧基)-4-甲基香豆素 | 175135-91-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 中文名称: 6-(3-氯丙氧基)-4-甲基香豆素
• 英文名称: 6-(3-Chloropropoxy)-4-methylcoumarin
• 英文别名: 6-(3-chloropropoxy)-4-methylchromen-2-one
• CAS: 175135-91-8
• 化学式: C₁₃H₁₃ClO₃
• 分子量: 252.69
• InChiKey: AIFJUEQYVRXVBT-UHFFFAOYSA-N

物化性质

• 沸点：
  427.3±45.0 °C(Predicted)
• 密度：
  1.241±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2932209090

文献信息

• USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY
  申请人：Novabiotics Limited

  公开号：EP2049511A1

  公开（公告）日：2009-04-22
• POLYPEPTIDES AND THEIR USE
  申请人：Novabiotics Limited

  公开号：EP2825261A1

  公开（公告）日：2015-01-21
• Polypeptides and Their Use
  申请人：O'NEIL Deborah

  公开号：US20140155321A1

  公开（公告）日：2014-06-05

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.
• [EN] USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY<br/>[FR] COMPOSÉS ET LEUR UTILISATION
  申请人：NOVABIOTICS LTD

  公开号：WO2007141513A1

  公开（公告）日：2007-12-13

  [EN] The invention provides coumarin compounds, in particular glycosidic coumarin compounds, useful in the treatment of dermatophyte fungal infections.
  [FR] La présente invention concerne des composés de coumarine, en particulier des composés de coumarine glycosidique, utiles dans le traitement d'infections fongiques par des dermatophytes.
• [EN] POLYPEPTIDES AND THEIR USE<br/>[FR] POLYPEPTIDES ET LEUR UTILISATION
  申请人：NOVABIOTICS LTD

  公开号：WO2013136040A1

  公开（公告）日：2013-09-19

  The present invention relates to a polypeptide or a product comprising said polypeptide for use in the treatment and/or prevention of a fungal infection caused by Malassezia spp. and/or a Malassezia spp associated condition wherein the polypeptide comprises a sequence of about 25 to 200 amino acids wherein substantially all of the amino acids in said sequence are lysine; pharmaceutical compositions comprising said polypeptide or product and uses thereof.