[(2S)-4-(ethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl]carbamic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: [(2S)-4-(ethylamino)-3-hydroxy-4-oxo-1-phenylbutan-2-yl]carbamic acid
• 化学式: C₁₃H₁₈N₂O₄
• 分子量: 266.29
• InChiKey: IRKNNORCISZGKD-VUWPPUDQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  98.7
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Dipeptidyl ketoamide compounds and their use for the treatment and/or prevention of fat accumulation
  申请人：LANDSTEINER GENMED, S.L.

  公开号：US10294269B2

  公开（公告）日：2019-05-21

  The present invention relates to the use of dipeptidyl ketoamide compounds for preventing accumulation of triglycerides in adipose tissue or for reducing the amount of triglycerides in adipose tissue in a subject in need thereof and to novel dipeptidyl ketoamide compounds.

  本发明涉及二肽基酮酰胺化合物用于防止脂肪组织中甘油三酯的积累，或用于减少有需要的受试者脂肪组织中甘油三酯的含量，还涉及新型二肽基酮酰胺化合物。
• DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION
  申请人：LANDSTEINER GENMED, S.L.

  公开号：EP3191112A2

  公开（公告）日：2017-07-19
• INDAZOLYL- AND INDOLYL-BENZAMIDE DERIVATIVES
  申请人：Esanex, Inc.

  公开号：EP3191473A1

  公开（公告）日：2017-07-19
• [EN] INDAZOLYL- AND INDOLYL-BENZAMIDE DERIVATIVES<br/>[FR] DÉRIVÉS INDAZOLYL- ET INDOLYL-BENZAMIDE
  申请人：ESANEX INC

  公开号：WO2016040809A1

  公开（公告）日：2016-03-17

  useful in the treatment and/or prevention of diseases and/or conditions related to cell proliferation, such as cancer, infection, inflammation and inflammation-associated disorders, and conditions associated with angiogenesis.
• [EN] DIPEPTIDYL KETOAMIDE COMPOUNDS AND THEIR USE FOR THE TREATMENT AND/OR PREVENTION OF FAT ACCUMULATION<br/>[FR] COMPOSÉS DIPEPTIDYL-CÉTOAMIDE ET LEUR UTILISATION POUR LE TRAITEMENT ET/OU LA PRÉVENTION DE L'ACCUMULATION DE GRAISSE
  申请人：LANDSTEINER GENMED S L

  公开号：WO2016038040A2

  公开（公告）日：2016-03-17

  The present invention relates to the use of dipeptidyl ketoamide compounds for preventing accumulation of triglycerides in adipose tissue or for reducing the amount of triglycerides in adipose tissue in a subject in need thereof and to novel dipeptidyl ketoamide compounds.