(1S,2S)-3-azido-1-[3-(cyclohexylmethoxy)phenyl]propane-1,2-diol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (1S,2S)-3-azido-1-[3-(cyclohexylmethoxy)phenyl]propane-1,2-diol
• 化学式: C16H23N3O3
• 分子量: 305.37
• InChiKey: QXAMOXLLDGLIGQ-HOTGVXAUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  64
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Alkoxy compounds for disease treatment
  申请人：Scott Ian L.

  公开号：US20090326074A1

  公开（公告）日：2009-12-31

  The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

  本发明涉及治疗神经退行性疾病和疾病的组合物和方法，特别是眼科疾病和疾病的组合物和方法。本文提供了烷氧基衍生物化合物和包含这些化合物的药物组合物。这些组合物可用于治疗和预防眼科疾病和疾病，包括年龄相关性黄斑变性（AMD）和Stargardt病。
• Alkoxy Compounds for Disease Treatment
  申请人：Scott Ian L.

  公开号：US20120129894A1

  公开（公告）日：2012-05-24

  The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

  本发明通常涉及用于治疗神经退行性疾病和疾病的组合物和方法，特别是眼科疾病和疾病。本文提供了烷氧基衍生物化合物和包含这些化合物的制药组合物。这些化合物对于治疗和预防眼科疾病和疾病，包括年龄相关性黄斑部退化（AMD）和Stargardt病是有用的。
• ALKOXY COMPOUNDS FOR DISEASE TREATMENT
  申请人：Scott Ian L.

  公开号：US20130197096A1

  公开（公告）日：2013-08-01

  The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

  本发明一般涉及用于治疗神经退行性疾病和疾病的组合物和方法，特别是用于治疗眼科疾病和疾病。本文提供了烷氧基衍生物化合物和包含这些化合物的制药组合物。该组合物可用于治疗和预防眼科疾病和疾病，包括年龄相关性黄斑部退化（AMD）和Stargardt病。
• ALKOXYPHENYLPROPYLAMINES FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION
  申请人：Acucela, Inc.

  公开号：EP3210966A1

  公开（公告）日：2017-08-30

  The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are alkoxyl derivative compounds and pharmaceutical compositions comprising these compounds. The subject compositions are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

  本发明一般涉及治疗神经退行性疾病和失调，特别是眼科疾病和失调的组合物和方法。本发明提供了烷氧基衍生物化合物和包含这些化合物的药物组合物。所述组合物可用于治疗和预防眼科疾病和失调，包括老年性黄斑变性（AMD）和Stargardt病。
• US7982071B2
  申请人：——

  公开号：US7982071B2

  公开（公告）日：2011-07-19