Ethyl 3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Ethyl 3-aminobicyclo[2.2.1]hept-5-ene-2-carboxylate
• 化学式: C₁₀H₁₅NO₂
• mdl: MFCD10039779
• 分子量: 181.23
• InChiKey: SMNRHCYSKKEJLS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE
  申请人：Hurley Timothy Brian

  公开号：US20090325948A1

  公开（公告）日：2009-12-31

  The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as bacterial infection.

  本发明涉及选择性和/或有效抑制UPPS的化合物。除了抑制UPPS的化合物外，本发明还提供包含这些化合物的药物组合物以及使用这些化合物治疗细菌性疾病，如细菌感染的方法。
• Neutralised cationic polymer, composition containing said polymer and a cosmetic treatment method
  申请人：Mougin Nathalie

  公开号：US10004923B2

  公开（公告）日：2018-06-26

  The invention relates to an ethylene cationic polymer comprising at least one primary, secondary or tertiary protonable amine function which is at least partially neutralized by a polymer organic acid neutralizing agent which contains at least one carboxylic, sulphonic and/or phosphonic acid function. Said invention also relates to a cosmetic or pharmaceutical composition comprising said neutralized polymer in a physiologically acceptable medium, in particular, cosmetically or pharmaceutically acceptable medium. A method for cosmetically treating keratinic materials, such as a body of face skin, nails, hairs, eyebrows and/or eyelashes, consisting in applying the inventive cosmetic composition to said keratinic materials is also disclosed.

  本发明涉及一种乙烯阳离子聚合物，它包含至少一个伯、仲或叔质子胺官能团，该官能团至少部分被聚合物有机酸中和剂中和，该聚合物有机酸中和剂包含至少一个羧酸、磺酸和/或膦酸官能团。本发明还涉及一种化妆品或药物组合物，该组合物包含在生理上可接受的介质（尤其是化妆品或药物上可接受的介质）中的所述中和聚合物。本发明还公开了一种对角质材料（如面部皮肤、指甲、毛发、眉毛和/或睫毛）进行美容处理的方法，包括将本发明的化妆品组合物涂抹在所述角质材料上。
• [EN] INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE<br/>[FR] INHIBITEURS DE L'UNDÉCAPRÉNYL PYROPHOSPHATE SYNTHASE
  申请人：NOVARTIS AG

  公开号：WO2008014307A2

  公开（公告）日：2008-01-31

  [EN] The present invention relates to compounds that are selective and/or potent inhibitors of UPPS. In addition to compounds which inhibit UPPS, the invention also provides pharmaceutical compositions comprising these compounds and methods of using these compounds for treating bacterial disease, such as bacterial infection.
  [FR] L'invention concerne des composés qui sont des inhibiteurs sélectifs et/ou puissants de l'undécaprényl pyrophosphate systhase (UPPS). Outre les composants qui inhibent l'UPPS, l'invention concerne des compositions pharmaceutiques comprenant ces composés ainsi que des procédés d'utilisation de ces composés dans le traitement de maladies bactériennes, telles qu'une infection bactérienne.