Ethyl 6-methylhept-3-enoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Ethyl 6-methylhept-3-enoate
• 英文别名: ethyl 6-methylhept-3-enoate
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.25
• InChiKey: OSQKTCPQXZHJRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Intermediates for the preparation of Pregabalin and process for their preparation
  申请人：Chemo Ibérica, S.A.

  公开号：EP2110372A1

  公开（公告）日：2009-10-21

  The present invention relates to intermediates useful for the preparation of Pregabalin and to a process for their preparation.

  本发明涉及用于制备普雷加巴林的中间体以及它们的制备方法。
• [EN] INTERMEDIATES FOR THE PREPARATION OF PREGABALIN AND PROCESS FOR THEIR PREPARATION<br/>[FR] INTERMÉDIAIRES POUR LA PRÉPARATION DE PRÉGABALINE ET LEUR PROCÉDÉ DE PRÉPARATION
  申请人：CHEMO IBERICA SA

  公开号：WO2009127560A1

  公开（公告）日：2009-10-22

  The present invention relates to intermediates useful for the preparation of Pregabalin and to a process for their preparation.

  本发明涉及用于制备普瑞巴林的中间体以及其制备过程。
• Methods for producing substituted acrylic acid esters and use of the latter for producing substituted $G (G)-amino acids
  申请人：Przewosny Thomas Michael

  公开号：US20050043565A1

  公开（公告）日：2005-02-24

  The invention relates to methods for producing substituted acrylic acid esters and to the use of the latter for producing substituted γ-amino acids, such as gabapentin and pregabalin. The substituted acrylic acid esters are produced by Wadsworth-Emmons olefination with trialkyl phosphonoacetate in the presence of alkali carbonate as the base, in an aqueous solvent.

  本发明涉及制备取代丙烯酸酯的方法，以及利用后者制备取代γ-氨基酸，例如加巴喷丁和普瑞巴林。所述取代丙烯酸酯是通过在水溶剂中以三烷基膦酸乙酯为沃尔茨沃思-艾蒙斯烯化试剂，在碱性碳酸盐存在下作为碱催化剂进行制备的。
• Pregabalin intermediates and process for preparing them and Pregabalin
  申请人：Chemo Ibérica, S.A.

  公开号：EP2053040A1

  公开（公告）日：2009-04-29

  The present invention provides novel compounds, which are especially useful as intermediates for the preparation of Pregabalin. The invention also relates to process for preparing these intermediates and Pregabalin.

  本发明提供了新型化合物，它们尤其可用作制备普瑞巴林的中间体。本发明还涉及制备这些中间体和普瑞巴林的工艺。
• US7141695B2
  申请人：——

  公开号：US7141695B2

  公开（公告）日：2006-11-28