benzyl N-[(1S)-3-methyl-1-[(1-oxo-3-phenylpropan-2-yl)carbamoyl]butyl]carbamate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: benzyl N-[(1S)-3-methyl-1-[(1-oxo-3-phenylpropan-2-yl)carbamoyl]butyl]carbamate
• 英文别名: benzyl N-[(2S)-4-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]pentan-2-yl]carbamate
• 化学式: C₂₃H₂₈N₂O₄
• 分子量: 396.5
• InChiKey: CSKGFHNQMOIAFM-LBAQZLPGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  29
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  84.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] PROTEASOME INHIBITORS<br/>[FR] INHIBITEURS DE PROTÉASOME
  申请人：MAYO FOUND MEDICAL EDUCATION & RES

  公开号：WO2021072212A1

  公开（公告）日：2021-04-15

  In some embodiments, the present disclosure provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt thereof. In some embodiments, the present disclosure provides a compound of Formula (II) as described herein, or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions comprising the compound of Formula (I) or Formula (II), and methods of treating cancer using the compound of Formula (I) or Formula (II) are also provided.