4-(4-chlorophenoxy)-2-(trifluoromethyl)benzaldehyde | 1518092-44-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-chlorophenoxy)-2-(trifluoromethyl)benzaldehyde
• 英文别名: 4-(4-Chlorophenoxy)-2-(trifluoromethyl)benzaldehyde
• CAS: 1518092-44-8
• 化学式: C₁₄H₈ClF₃O₂
• 分子量: 300.665
• InChiKey: ISRUFDYXXSHRRO-UHFFFAOYSA-N

物化性质

• 沸点：
  357.7±42.0 °C(Predicted)
• 密度：
  1.384±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-(4-chlorophenoxy)-2-(trifluoromethyl)benzaldehyde 在 pyridinium chlorochromate 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 2.0h， 生成 1-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]hex-5-en-1-one
  参考文献：
  名称：

  [EN] NEW SUBSTITUTED TRIAZOLES AND IMIDAZOLES AND THEIR USE AS FUNGICIDES
  [FR] NOUVEAUX TRIAZOLES ET IMIDAZOLES SUBSTITUÉS ET LEUR UTILISATION EN TANT QUE FONGICIDES

  摘要：

  新的取代三唑和咪唑及其作为杀菌剂的用途。本发明涉及公式I所定义的新的取代三唑和咪唑化合物，以及其N-氧化物和盐，它们的制备和制备它们的中间体。本发明还涉及使用这些化合物来对抗有害真菌和至少包含一种这样的化合物的种子涂层，以及包含至少一种这样的化合物的组合物。

  公开号：

  WO2014095534A1

文献信息

• Inhibitors of bacterial RNA polymerase: arylpropanoyl, arylpropenoyl, and arylcyclopropanecarboxyl phloroglucinols
  申请人：Rutgers, The State University of New Jersey

  公开号：US10450292B2

  公开（公告）日：2019-10-22

  The invention provides compounds that are inhibitors of bacterial RNA polymerase. The invention also provides compositions comprising such compounds, methods of making such compounds, and methods of using said compounds. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.

  本发明提供的化合物是细菌 RNA 聚合酶的抑制剂。本发明还提供了包含此类化合物的组合物、制造此类化合物的方法以及使用所述化合物的方法。本发明可应用于控制细菌基因表达、控制细菌生长、抗菌化学和抗菌治疗。
• INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS
  申请人：Rutgers, The State University of New Jersey

  公开号：US20190023682A1

  公开（公告）日：2019-01-24

  The invention provides compounds that are inhibitors of bacterial RNA polymerase. The invention also provides compositions comprising such compounds, methods of making such compounds, and methods of using said compounds. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.
• [EN] INHIBITORS OF BACTERIAL RNA POLYMERASE: ARYLPROPANOYL, ARYLPROPENOYL, AND ARYLCYCLOPROPANECARBOXYL PHLOROGLUCINOLS<br/>[FR] INHIBITEURS D'ARN POLYMÉRASE BACTÉRIENNE : ARYL PROPANOYLE, ARYL PROPÉNOYLE ET ARYL CYCLOPROPANE CARBOXYL PHLOROGLUCINOLS
  申请人：UNIV RUTGERS

  公开号：WO2017100645A2

  公开（公告）日：2017-06-15

  The invention provides compounds that are inhibitors of bacterial RNA polymerase. The invention also provides compositions comprising such compounds, methods of making such compounds, and methods of using said compounds. The invention has applications in control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, and antibacterial therapy.
• [EN] NEW SUBSTITUTED TRIAZOLES AND IMIDAZOLES AND THEIR USE AS FUNGICIDES<br/>[FR] NOUVEAUX TRIAZOLES ET IMIDAZOLES SUBSTITUÉS ET LEUR UTILISATION EN TANT QUE FONGICIDES
  申请人：BASF SE

  公开号：WO2014095534A1

  公开（公告）日：2014-06-26

  New substituted triazoles and imidazoles and their use as fungicides The present invention relates to new substituted triazoles and imidazoles compounds of formula I as defined in the description, and the N-oxides, and salts thereof, their preparation and intermediates for preparing them. The invention also relates to the use of these compounds for combating harmful fungi and seed coated with at least one such compound and also to compositions comprising at least one such compound.

  新的取代三唑和咪唑及其作为杀菌剂的用途。本发明涉及公式I所定义的新的取代三唑和咪唑化合物，以及其N-氧化物和盐，它们的制备和制备它们的中间体。本发明还涉及使用这些化合物来对抗有害真菌和至少包含一种这样的化合物的种子涂层，以及包含至少一种这样的化合物的组合物。