3-(Phenoxymethyl)thiophene-2-carbothioamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(Phenoxymethyl)thiophene-2-carbothioamide
• 化学式: C₁₂H₁₁NOS₂
• mdl: MFCD01934471
• 分子量: 249.4
• InChiKey: IOCTVBGDCAMSIF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.083
• 拓扑面积：
  95.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• TGFß SIGNALING INDEPENDENT NAÏVE INDUCED PLURIPOTENT STEM CELLS, METHODS OF MAKING AND USE
  申请人：HONG GUAN Ltd.

  公开号：US20170191038A1

  公开（公告）日：2017-07-06

  Provided is a cocktail of factors for converting/reprogramming non-naïve pluripotent stem cells into TGFβ signaling-independent (TSI) naïve induced pluripotent stem cells (iPSCs). Also provided are methods for reprograming a non-naïve PSC into a TSI naïve iPSC by contacting the cell to be reprogrammed with effective amounts of compounds for a sufficient period of time to reprogram the cell into a TSI naïve iPSC.
• [EN] TGFβ SIGNALING INDEPENDENT NAÏVE INDUCED PLURIPOTENT STEM CELLS, METHODS OF MAKING AND USE<br/>[FR] CELLULES SOUCHES PLURIPOTENTES INDUITES NAÏVES INDÉPENDANTES DE LA SIGNALISATION TGFSS, PROCÉDÉS DE PRODUCTION ET UTILISATION
  申请人：HONG GUAN LTD

  公开号：WO2016045550A1

  公开（公告）日：2016-03-31

  Provided is a cocktail of factors for converting/reprogramming non-naïve pluripotent stem cells into TGFβ signaling-independent (TSI) naïve induced pluripotent stem cells (iPSCs). Also provided are methods for reprograming a non-naïve PSC into a TSI naïve iPSC by contacting the cell to be reprogrammed with effective amounts of compounds for a sufficient period of time to reprogram the cell into a TSI naïve iPSC.