Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes.
本文描述了可与核医学中使用的
金属放射性同位素高亲和力结合的苷酸-
金属
螯合剂组合。高亲和力的蚕豆素-
金属
螯合剂组合包括多种
螯合剂骨架排列,并带有能与
金属配位的官能团。蚕豆蛋白-
金属
螯合剂组合可用于输送放射性核素,以达到成像和治疗的目的。